A systematic review of current progresses in the nucleic acid-based therapies for neurodegeneration with implications for alzheimer's disease

M Ghaffari, N Sanadgol… - Mini Reviews in Medicinal …, 2020 - ingentaconnect.com
… highlight the potential of nucleic acid-based therapies (NA-BTs). Alzheimer’s Disease (AD) is
… is a cause of death and the most common form of dementia is Alzheimer's disease (AD) [1]. …

Functionalized nanoparticles to deliver nucleic acids to the brain for the treatment of Alzheimer's disease

CE Muolokwu, B Chaulagain, A Gothwal… - Frontiers in …, 2024 - frontiersin.org
… This progress underscores the promise of leveraging nucleic acid-based approaches in
developing innovative treatments for AD. Nonetheless, utilizing nucleic acids as therapeutic …

Nucleic Acid-Based Strategies to Treat Neurodegenerative Diseases

S Panda, O Chatterjee, S Chatterjee - Nucleic Acid Biology and its …, 2023 - Springer
… , Parkinson’s disease, amyotrophic lateral sclerosis, etc. Here, we will discuss the
important nucleic acid-based therapies to treat neurodegenerative diseases along with the …

New RNA-based breakthroughs in Alzheimer's disease diagnosis and therapeutics

M Riscado, B Baptista, F Sousa - Pharmaceutics, 2021 - mdpi.com
… a wide range of diseases, with Alzheimer’s disease (AD), Vascular Dementia, dementia with
Lewy bodies, Frontotemporal Dementia and Parkinson’s Disease being the most relevant [2,…

[HTML][HTML] Small-molecule theranostics in Alzheimer's disease

Á Sarabia-Vallejo, P López-Alvarado… - European Journal of …, 2023 - Elsevier
… In recent years, theranostic agents have emerged as an … We review here the area of
small-molecule theranostic agents … and significant impact that theranostics can be expected to …

Nucleic Acid-Based Nanocarriers

AK Chakraborty - Nanocarriers for Drug Delivery, 2019 - Elsevier
… There are many obstacles to the delivery of drugs into neurons of the brain for its regeneration
in Alzheimer’s disease (AD), which severely damages memory and cognitive functions of …

[图书][B] Nucleic Acid Nanotheranostics: Biomedical Applications

M Filice, J Ruiz-Cabello - 2019 - books.google.com
… and therapy) and nucleic acid-based therapies are two exciting … specificity have found many
theranostics applications, but of … gene are highly associated with Alzheimer disease, and are …

Advances in Antioxidant Nanomedicines for Imaging and Therapy of Alzheimer's Disease

I Hasan, B Guo, J Zhang, C Chang - Antioxidants & Redox …, 2024 - liebertpub.com
… Amyloid-β oligomer-targeted gadolinium-based NIR/MR dual-modal theranostic
nanoprobe for Alzheimer's disease. Adv Funct Mater 2020;30(16):909529; doi: 10.1002/adfm.…

Nanodelivery of nucleic acids

BB Mendes, J Conniot, A Avital, D Yao… - Nature reviews …, 2022 - nature.com
There is growing need for a safe, efficient, specific and non-pathogenic means for delivery
of gene therapy materials. Nanomaterials for nucleic acid delivery offer an unprecedented …

[PDF][PDF] DNA NANOTECHNOLOGY: A STEP TOWARDS THERANOSTIC PLATFORM FOR VARIOUS DISEASES

P SHRIVASTAVA, NL DHAS, DRTA MEHTA - 26 th ISCB Inte - researchgate.net
… TLR4 has also been reported to play a role during neurodegenerative disorders,
including Alzheimer's disease, multiple sclerosis and Parkinson's disease and related α-…