Ocular pharmacology

GD Novack, AL Robin - The Journal of Clinical Pharmacology, 2024 - Wiley Online Library
… Patients have issues with the administration of an exact amount (without waste) and without
contamination (eg, using fingers to place a specific amount of gel onto the eye). In addition, …

Ocular drug delivery: present innovations and future challenges

V Gote, S Sikder, J Sicotte, D Pal - Journal of Pharmacology and …, 2019 - ASPET
ophthalmic medications include the use of topical eye drops … growth factor agent for
treatment of anterior and posterior … hydrogels with specific binding affinity used for making drug-…

Advances and limitations of drug delivery systems formulated as eye drops

C Jumelle, S Gholizadeh, N Annabi, R Dana - Journal of Controlled …, 2020 - Elsevier
drugs to the anterior segment of the eye. Therefore, eye drops are the treatment of choice
for many ocular diseases such as infection, inflammation, glaucoma, dry eye and allergy, …

EULAR recommendations for the management of Sjögren's syndrome with topical and systemic therapies

M Ramos-Casals, P Brito-Zerón… - Annals of the …, 2020 - ard.bmj.com
… According to the SLR results, for the treatment of ocular dryness we do not recommend the …
defining specific treatment targets (especially searching for remission in non-systemic features…

Glaucoma: current treatment and impact of advanced drug delivery systems

KS Yadav, R Rajpurohit, S Sharma - Life sciences, 2019 - Elsevier
drugs very much attractive to patients and physician [32]. However, prostaglandins have
local ocular side effects like irritation, redness of eye … direct the drugs to target specific ocular

Ocular adverse events following use of immune checkpoint inhibitors for metastatic malignancies

CW Noble, SS Gangaputra, IA Thompson… - Ocular immunology …, 2020 - Taylor & Francis
… Due to limited sample size, we were unable to draw any conclusion regarding specific ocular
irAEs being associated with any specific drug or drug combination. We also were not able …

Drug delivery to the posterior segment of the eye: biopharmaceutic and pharmacokinetic considerations

R Varela-Fernández, V Díaz-Tomé… - Pharmaceutics, 2020 - mdpi.com
drug administration is always selected to deliver to the posterior ocular segment due to the
possibility of overcoming systemic exposure and obtaining high drug levels into the vitreous …

Nanocarriers for ocular drug delivery: Current status and translational opportunity

S Gorantla, VK Rapalli, T Waghule, PP Singh… - RSC …, 2020 - pubs.rsc.org
… Advances in nanomedicine have facilitated controlled and target-specific drug delivery to
ocular tissues to treat ocular diseases. Therapeutic delivery through nanocarriers can reduce …

[HTML][HTML] Design principles of ocular drug delivery systems: importance of drug payload, release rate, and material properties

A Subrizi, EM Del Amo, V Korzhikov-Vlakh… - Drug discovery today, 2019 - Elsevier
… , systematic, guidance for ocular drug dosing and delivery system design. We integrate ocular
… system selection to augment decision-making and initial drug delivery system design in …

[HTML][HTML] Ocular manifestations of COVID-19: a systematic review and meta-analysis

N Nasiri, H Sharifi, A Bazrafshan, A Noori… - … of ophthalmic & vision …, 2021 - ncbi.nlm.nih.gov
… this systematic review and meta-analysis, we investigated the prevalence of ocular manifestations
… The reviewers resolved the disagreements on the process of study selection through …