YAP/TAZ regulate elevation and bone formation of the mouse secondary palate

AF Goodwin, CP Chen, NT Vo… - Journal of Dental …, 2020 - journals.sagepub.com
… of YAP/TAZ in secondary palate development by disrupting their … with the Osr2 Cre driver,
the PSs appeared similar in the Yap … Ibsp, which encodes a major protein component of bone, …

Gene regulatory networks and signaling pathways in palatogenesis and cleft palate: a comprehensive review

HJ Won, JW Kim, HS Won, JO Shin - Cells, 2023 - mdpi.com
… The secondary palate develops as paired protrusions that growOdd-skipped related 2
(Osr2) is decreased in the palatal … Osr1 and Osr2 are zinc-finger transcription factor encoding

Revisiting the embryogenesis of lip and palate development

NL Hammond, MJ Dixon - Oral Diseases, 2022 - Wiley Online Library
… during secondary palate development and imply … Odd-skipped-related 2 is an intrinsic
regulator of palatal mesenchymal cell proliferation with Osr2 −/− mice displaying cleft palate

The Function and Regulatory Network of Pax9 Gene in Palate Development

R Li, Z Chen, Q Yu, M Weng… - Journal of dental …, 2019 - journals.sagepub.com
… genes (Osr2 and Bmpr1a) leading to deficient palate growth, … between PAX9 and genes
encoding the OSR2, TGFβ3, and … PAX9 might participate in the regulation of palate fusion. This …

Downregulation of odd-skipped related 2, a novel regulator of epithelial-mesenchymal transition, enables efficient somatic cell reprogramming

LPH Anh, K Nishimura, A Kuno, NT Linh, T Kato… - Stem Cells, 2022 - academic.oup.com
… that acts through induction of transforming growth factor-β (TGF… that downregulation of
odd-skipped related 2 (Osr2) is crucial … Mouse Osr2 gene encodes a zinc-finger protein related to …

Spatiotemporal Gene Expression Regions along the Anterior–Posterior Axis in Mouse Embryos before and after Palatal Elevation

A Nagasaka, K Sakiyama, Y Bando… - International Journal of …, 2022 - mdpi.com
… The mammalian secondary palate is formed through complex developmental processes: …
of the Drosophila odd-skipped family developmental regulators [22,23]. Osr2 was expressed …

Molecular mechanisms of palate development

XUCHU Xu-feng - Acta Anatomica Sinica, 2021 - jpxb.bjmu.edu.cn
Odd-skipped related 2 (Osr2) encodes a key intrinsic regulator of secondary palate growth
and … Identification of Osr2 transcriptional target genesin palatedevelopment [J]. JDent Resꎬ …

odd skipped-related 2 as a novel mark for labeling the proximal convoluted tubule within the zebrafish kidney

W Yang, X Liu, Z He, Y Zhang, X Tan, C Liu - Heliyon, 2024 - cell.com
… of odd-skipped-related 2 (osr2, which encodes an odd-skipped … To gain insight into the role
of osr2 in PCT morphogenesis, … development, we can use EGFP to track PCT development, …

Conditional deletion of Bmp2 in cranial neural crest cells recapitulates Pierre Robin sequence in mice

Y Chen, Z Wang, YP Chen, Y Zhang - Cell and tissue research, 2019 - Springer
… The development of the secondary palate can be divided into … Deletion of Tak1, a key
regulator of TGFβ signaling, in CNC … in the palate, our study shows it is not the intrinsic regulator

Osr2 functions as a biomechanical checkpoint to aggravate CD8+ T cell exhaustion in tumor

J Zhang, J Li, Y Hou, Y Lin, H Zhao, Y Shi, K Chen… - Cell, 2024 - cell.com
… In this study, we discover that a transcription factor (TF) Odd-skipped related 2 (Osr2), …
Odd-skipped related 2 (Osr2) encodes a key intrinsic regulator of secondary palate growth