Implications of estrogen and its receptors in colorectal carcinoma

PK Das, J Saha, S Pillai, AKY Lam, V Gopalan… - Cancer …, 2023 - Wiley Online Library
Estrogens and their receptors show either … of estrogen and its receptors may provide prospects
for improved CRC management. In this review, we discuss the roles of estrogen receptors

Targeting estrogen receptors in colorectal cancer

JW Maingi, S Tang, S Liu, W Ngenya, E Bao - Molecular Biology Reports, 2020 - Springer
… Abnormal estrogen receptor signaling may increase the risk of development of a variety of
diseases including colorectal cancer (CRC). Estrogen receptor beta (ERβ) is the predominant …

Estrogen receptors in colorectal cancer: Facts, novelties and perspectives

I Ditonno, G Losurdo, M Rendina, M Pricci, B Girardi… - Current …, 2021 - mdpi.com
Colorectal cancer (CRC) is the second cause of cancer-related death in both sexes … role
for estrogens has been hypothesized. Indeed, two isoforms of nuclear estrogen receptors (ER) …

Tumour‐suppressive effect of oestrogen receptor β in colorectal cancer patients, colon cancer cells, and a zebrafish model

G Topi, SR Satapathy, P Dash… - The Journal of …, 2020 - Wiley Online Library
… 15-PGDH in human colon cancer cells could be … of oestrogen in CRC mediated via
oestrogen receptor beta (ERβ) [15, 16]. We recently reported that high ERβ expression in cancer

Prognostic value of estrogen receptor-α and progesterone receptor in curatively resected colorectal cancer: A retrospective analysis with independent validations

SB Ye, YK Cheng, L Zhang, XP Wang, L Wang, P Lan - BMC cancer, 2019 - Springer
… The aim of our study was to investigate the potential impact of estrogen receptor-α (ER-α)
and progesterone receptor (PR) on the prognosis of colorectal cancer (CRC) patients who …

The prognostic and therapeutic role of hormones in colorectal cancer: a review

S Nikolaou, S Qiu, F Fiorentino, S Rasheed… - Molecular biology …, 2019 - Springer
Colorectal cancer (CRC) is one of the commonest cancers in Western society with a poor
prognosis in patients with advanced disease. Targeted therapy is of increasing interest and …

[HTML][HTML] Profiling estrogen, progesterone, and androgen receptors in colorectal cancer in relation to gender, menopausal status, clinical stage, and tumour sidedness

B Refaat, A Aslam, S Idris, AH Almalki… - Frontiers in …, 2023 - frontiersin.org
Background Although estrogen (ERα/ERβ), progesterone (PGR), and androgen (AR)
receptors are pathologically altered in colorectal cancer (CRC), their simultaneous expression …

[HTML][HTML] Estrogen and progesterone expression in colorectal carcinoma: A clinicopathological study

AAEG Abd ElLateef, AES Mohamed… - … Journal of Cancer …, 2020 - ncbi.nlm.nih.gov
… Sex steroids have been suggested to influence colorectal cancer (CRC) carcinogenesis.
Also, exposure to exogenous hormones might contribute to its incidence. This study conducted …

Investigating the factors associated with the level of expression of estrogen and progesterone receptors in patients suffering from colorectal cancer

S Salehi far, M Soltani, M Zardast… - Journal of Cancer …, 2021 - Wiley Online Library
of estrogen plus progesterone receptors and grade of cancer; … grades of colorectal cancer,
the level of expression of estrogen as … estrogen receptor and decreased colorectal cancer [32]. …

[HTML][HTML] Significance of G protein-coupled estrogen receptor in the pathophysiology of irritable bowel syndrome, inflammatory bowel diseases and colorectal cancer

D Jacenik, WM Krajewska - Frontiers in Endocrinology, 2020 - frontiersin.org
… It has been shown that the G protein-coupled estrogen receptor can modulate the … ulcerative
colitis as well as colorectal cancer. The G protein-coupled estrogen receptor appears to be a …