Preclinical and clinical development of noncoding RNA therapeutics for cardiovascular disease
… in pigs following myocardial infarction has been documented. … organs and sometimes
exhibit species-specific effects. … ability to raise an immune response. Cardiac specific delivery …
exhibit species-specific effects. … ability to raise an immune response. Cardiac specific delivery …
[HTML][HTML] Macrophages: First guards in the prevention of cardiovascular diseases
MI Nasser, S Zhu, H Huang, M Zhao, B Wang, H Ping… - Life sciences, 2020 - Elsevier
… role in the innate immune response, inflammation, and host defense. In response to different
… reactions and limiting adverse matrix remodeling after myocardial ischemia and reperfusion…
… reactions and limiting adverse matrix remodeling after myocardial ischemia and reperfusion…
relevant clinical pathology resources: Emphasis on mice, rats, rabbits, dogs, Minipigs, and non-human primates
L Bau-Gaudreault, T Arndt, A Provencher… - ILAR …, 2021 - academic.oup.com
… for investigative or biomedical research and for preclinical toxicity and safety assessment
in laboratory animals is a distinct specialty requiring an understanding of species specific and …
in laboratory animals is a distinct specialty requiring an understanding of species specific and …
The roles of Th cells in myocardial infarction
J Liu, F Liu, T Liang, Y Zhou, X Su, X Li, J Zeng… - Cell Death …, 2024 - nature.com
… This study indicates that Th9 cells may play a role in the inflammatory response following …
in the inflammatory response, Th17 cells may promote ECM remodeling after myocardial injury …
in the inflammatory response, Th17 cells may promote ECM remodeling after myocardial injury …
Beneficial effects of IL-4 and IL-6 on rat neonatal target cardiac cells
C Zogbi, NC Oliveira, D Levy, SP Bydlowski… - Scientific reports, 2020 - nature.com
… We speculate that the pattern of inflammatory response contributes to the regenerative …
Aurora et all observed different subtypes of macrophages in neonatal mice following myocardial …
Aurora et all observed different subtypes of macrophages in neonatal mice following myocardial …
Distinct longevity mechanisms across and within species and their association with aging
… immune response and cellular respiration. Signatures of long-lived species were positively
correlated with age-related changes and enriched for evolutionarily ancient essential genes, …
correlated with age-related changes and enriched for evolutionarily ancient essential genes, …
Glycogen synthase kinase-3β inhibition alleviates activation of the NLRP3 inflammasome in myocardial infarction
S Wang, X Su, L Xu, C Chang, Y Yao, S Komal… - Journal of Molecular and …, 2020 - Elsevier
… in heart dysfunction after myocardial infarction (MI). … inflammation and tissue damage [6].
IL-1β plays an important role in the inflammatory response following MI by regulating immune …
IL-1β plays an important role in the inflammatory response following MI by regulating immune …
Formation and growth of cardiac lymphatics during embryonic development, heart regeneration, and disease
D Gancz, G Perlmoter, K Yaniv - Cold Spring Harbor …, 2020 - cshperspectives.cshlp.org
… conserved with certain species-specific variations. In … cardiac muscle is damaged and
up to 1 billion cardiomyocytes (CMs) are lost. CM death triggers an inflammatory response …
up to 1 billion cardiomyocytes (CMs) are lost. CM death triggers an inflammatory response …
Considerations for the bioengineering of advanced cardiac in vitro models of myocardial infarction
… of the ischemic events following myocardial infarction. These … and fibroblasts exacerbate
the inflammatory response, while … to overcome the limitations that are species specific. [ 49 ] As …
the inflammatory response, while … to overcome the limitations that are species specific. [ 49 ] As …
Fluid therapy in dogs and cats with sepsis
F Montealegre, BM Lyons - Frontiers in Veterinary Science, 2021 - frontiersin.org
… Variations in the host immune response result in diverse … from the microvessels to the
myocardium, where they adhere (… humans as well as species-specific differences in blood volume …
myocardium, where they adhere (… humans as well as species-specific differences in blood volume …