[HTML][HTML] Cortisol regeneration in the fetal membranes, a coincidental or requisite event in human parturition?

WS Wang, CM Guo, K Sun - Frontiers in Physiology, 2020 - frontiersin.org
… subdivided into a trophoblast layer and a connective tissue layer adjacent to the amnion. The
cortisone inhibit LOX expression in human amnion fibroblasts, and the effect of cortisone is …

11β‐Hydroxysteroid dehydrogenase and the brain: Not (yet) lost in translation

J Seckl - Journal of Internal Medicine, 2024 - Wiley Online Library
… by markedly elevated cortisol:cortisone metabolites in urine [14]. … interconversion of active
cortisol and corticosterone to inert … Distinct ontogeny of glucocorticoid and mineralocorticoid …

[HTML][HTML] Enhancement of cortisol-induced SAA1 transcription by SAA1 in the human amnion

Y Lu, W Wang, Y Lin, J Lu, W Li… - Journal of molecular …, 2019 - jme.bioscientifica.com
… a crucial steroid produced locally in the fetal membranes at parturition, and the interaction
between cortisol and SAA1 in the feed-forward induction of SAA1 expression in humantissue. …

11β-hydroxysteroid dehydrogenases: A growing multi-tasking family

EP Gomez-Sanchez, CE Gomez-Sanchez - Molecular and cellular …, 2021 - Elsevier
… , a dehydrogenase, to interconvert the active glucocorticoids … , elevated serum cortisol/cortisone
ratio and low cortisone, as … MR-mediated functions during ontogeny is discussed further …

Prednisolone and prednisone pharmacokinetics in renal transplant recipients

RKH Skauby - 2022 - duo.uio.no
… Cortisol modulates cellular and tissue functions, and efficiently … Interconversion between
prednisolone and prednisone … The plasma cortisol /cortisone AUC0-24 ratio of 8 (6-15) …

[HTML][HTML] Metabolomics analysis of follicular fluid coupled with oocyte aspiration reveals importance of glucocorticoids in primate periovulatory follicle competency

S Ravisankar, CB Hanna, KE Brooks, MJ Murphy… - Scientific Reports, 2021 - nature.com
steroid dehydrogenases that interconvert these … cortisol:cortisone ratio in FF is an important
determinant of oocyte competency and that the intrafollicular levels of cortisol and cortisone

[HTML][HTML] Involvement of porcine and human carbonyl reductases in the metabolism of epiandrosterone, 11-oxygenated steroids, neurosteroids, and corticosteroids

S Endo, Y Morikawa, K Suenami, Y Sakai, N Abe… - The Journal of Steroid …, 2024 - Elsevier
interconversion of keto and hydroxy groups at positions 3, 11, 17 and 20 on the steroid nucleus
and its side chain, and play an important rolesteroid substrates are high in these tissues. …

Mechanisms for establishment of the placental glucocorticoid barrier, a guard for life

P Zhu, W Wang, R Zuo, K Sun - Cellular and Molecular Life Sciences, 2019 - Springer
Ontogeny studies show that the expression of 11β-HSD2 is … into cortisone by homogenized
human placental tissue dominates at all gestational ages, albeit a small amount of cortisone

Sex steroids and glucocorticoid ratios in Iberian lynx hair

A Azevedo, J Wauters, C Kirschbaum… - Conservation …, 2020 - academic.oup.com
steroid measurement that accounts for local interconversion … of cortisol, cortisone and
cortisol-cortisone ratio between wild-… cortisone to cortisol and is expressed, among other tissues, …

[HTML][HTML] Diurnal rhythmicity in breast-milk glucocorticoids, and infant behavior and sleep at age 3 months

AA Toorop, B van der Voorn, JJ Hollanders, LR Dijkstra… - Endocrine, 2020 - Springer
tissues have been demonstrated to harbor 11β HSD type 2, which converts cortisol into
cortisone … for the conversion of cortisone to cortisol, in infants implies that ingested cortisone may …