[PDF][PDF] The role of brain-derived neurotrophic factor (BDNF) in cognitive functions

D Silakarma, AAR Sudewi - Bali Medical Journal, 2019 - pdfs.semanticscholar.org
… affinity binding by NT-3, and trkC binds NT-3. Trk receptors … of BDNF mRNA in the hippocampus
and cerebral cortex. However, … The provision of BDNF or increasing endogenous BDNF

Neurotrophin-3 modulates synaptic transmission

E Hernández-Echeagaray - Vitamins and hormones, 2020 - Elsevier
… This chapter focuses role of NT-3 in the modulation of … shown to control axonal and dendritic
development as well as … demonstrated that NT-3 and BDNF locally regulated synaptic …

Is neurotrophin-3 (NT-3): a potential therapeutic target for depression and anxiety?

AS de Miranda, JLVM de Barros… - Expert Opinion on …, 2020 - Taylor & Francis
Endogenous BDNF and NT3 exhibit opposite actions in regulating dendritic growth of
pyramidal neurons from layers 4 and 6 of the developing ferret visual cortex [Citation71]. …

The role of dendritic brain-derived neurotrophic factor transcripts on altered inhibitory circuitry in depression

H Oh, SC Piantadosi, BR Rocco, DA Lewis… - Biological …, 2019 - Elsevier
… L-3′-UTR knockdown is sufficient to induce 1) dendritic shrinkage in cortical neurons, 2)
cell-specific MDD-like gene changes (including Sst downregulation), and 3) depressive- and …

[PDF][PDF] Transient deregulation of canonical wnt signaling in developing pyramidal neurons leads to dendritic defects and impaired behavior

B Viale, L Song, V Petrenko, ALW Combremont… - Cell reports, 2019 - cell.com
dendritic growth period (E21–P7), the thalamocortical inputs … regulation plays a role in
dendritic maturation of layer II … of other neurotrophins (eg, BDNF). Previous studies suggested …

Neurotrophin-3 from the dentate gyrus supports postsynaptic sites of mossy fiber-CA3 synapses and hippocampus-dependent cognitive functions

JW Tan, JJ An, H Deane, H Xu, GY Liao, B Xu - Molecular Psychiatry, 2024 - nature.com
… 1 h sequentially to quench endogenous peroxidases and expose … As it has been shown that
BDNF deficiency impairs adult … the entorhinal cortex form synapses with dendrites of granule …

Distinct effects of BDNF and NT-3 on the dendrites and presynaptic boutons of developing olfactory bulb GABAergic interneurons in vitro

V Nieto-Estévez, Ç Defterali, C Vicario - Cellular and Molecular …, 2022 - Springer
… In this sense, opposite effects of BDNF and NT-3 have been described in different layers
of the cerebral cortex: BDNF stimulates dendrite growth in layer 4 where it is inhibited by NT-3, …

Intervention of brain-derived neurotrophic factor and other neurotrophins in adult neurogenesis

FF Ribeiro, S Xapelli - Recent Advances in NGF and Related Molecules …, 2021 - Springer
… of neuronal differentiation, axonal and dendritic growth, and … as an endogenous ligand
by itself, or pro-BDNF can be … Contrary to NGF and BDNF, NT-3 is by far the most highly …

Overexpression of NT-3 in the hippocampus suppresses the early phase of the adult neurogenic process

N Kasakura, Y Murata, A Shindo, S Kitaoka… - Frontiers in …, 2023 - frontiersin.org
… of the hippocampus that receives cortical inputs from the entorhinal cortex and projects them
to the … of other types of IEGs and BDNF was enhanced by high levels of NT-3 in the DG. The …

Neurotrophins and Cell Death

A Shekari, C Mahadeo, N Sanwalka… - … Pediatrics: Genetic and …, 2023 - Springer
… While we know that endogenous NGF exists primarily as the … regulation of dendritic growth
of pyramidal neurons in the visual system during development suggests that BDNF and NT-3