… paper on formulation and design expert optimization of MET-… , consequences of process
parameters on the formulation of MET … Drug release of MET from the optimized formulation was …

… drugs, such as metformin-HCl, owing to its water solubility which facilitates sustained drug
release [20,… 2A and B and Table S1 show the optimization results and the output parameters of …

… and optimizing their drug-release characteristics. These … formulations, and all other formulations
showed PDI values … this study, displaying controlled drug release characteristics both in …

… an anti-diabetic drug (Metformin hydrochloride) within poly (… to optimize the effects of fours
factors (the amount of metformin … In this analysis, the desirability parameter was selected. The …

… optimized batch tablets were compared and it was observed that the optimized O-CDDS batch
(F-4) followed zero-order release … were evaluated and evaluation parameters were finding …

… detect the optimized formulation of metformin HCL bilosomes … are crucial parameters for
transdermal drug delivery. Increasing … formulated and evaluated as a novel topical drug delivery …

… as drug delivery systems have the ability to decrease drugs' … of optimized niosomal formulation
gel of metformin HCl (F 12 ) of … the polydispersity values of all investigated formulations. …

… model for release from the gel formulation. Based on the in vitro drug release results, we …
We could also investigate the influence of formulation parameters, such as lipid composition …

… of metformin hydrochloride (M-HCl). Design of experiments (DoE) was applied for multivariate
optimization of … Risk assessment was performed to identify the critical method parameters (…

… Controlled release drug delivery improves patient … , formulation optimization of metformin
HCl controlled release tablets … on the drug’s pharmacokinetic and physicochemical parameters. …