… Optogenetics enriches the neuroscientific tool set for … circuits in a manner which exceeds the
spatio-temporal precision … specificity of projection targeting (see text for details) compared to …

… at both the level of single neurons and cortical columns. However, … The ultra-fine temporal
precision of optogenetics makes it an … ) are another common chemogenetic toolbox that utilize …

… With this ever-evolving genetic toolbox, scientists are continuing … (A) Optogenetic stimulation
of a population of neurons at their … lack precise on/off control compared to optogenetics or …

… Towards this goal, we combined spatially precise optogenetic … monosynaptic connections
to supragranular (L2/3) neurons in … To determine if translaminar excitatory connections display …

… intricate neuronal circuits at a spatio-temporal precision … new tool set seem tempting, we
emphasize here the role of … time constants of onset <1 ms (see Figure 3b). Voltage deflections of …

… identified >1 connections, we obtained a precision = 0.50±… ±0.28, ranging from 0.8 to 3.3
(see Table 3). To examine how … Two-photon optogenetic toolbox for fast inhibition, excitation …

… -brain functional connectivity during optogenetic stimulation. … consistent detection of single
neurons throughout the entire … light and matter enables precise optical confinement of the …

… methodology by offering temporally precise readouts of neuronal activity in freely … (see “PVR
management procedure” below) using Signal processing toolbox and Statistics toolbox in …

… single neurons and their interactions. Simultaneous recordings from many neurons, preferably
identified by optogenetic … connections between excitatory and inhibitory neurons derived …

… the role of single neuronal types and single connection pathways in controlling precise aspects
of … in the main non-sensorimotor functions addressed using optogenetics (see Table 1). …