Who's afraid of the X? Incorporating the X and Y chromosomes into the analysis of DNA methylation array data
… The overall distribution of DNAme on the X chromosome showed … DNA methylation profiles
of the X and Y chromosome. All plots show raw (non-normalized) data after probe filtering. A …
of the X and Y chromosome. All plots show raw (non-normalized) data after probe filtering. A …
The role of DNA methylation in gene regulation
PA Bommarito, RC Fry - Toxicoepigenetics, 2019 - Elsevier
… DNA methylation and the underlying chromatin structure. The … significant decreases in total
DNA methylation content, with … X chromosomes have disparate amounts of DNA methylation…
DNA methylation content, with … X chromosomes have disparate amounts of DNA methylation…
Epigenetic and transcriptomic consequences of excess X‐chromosome material in 47, XXX syndrome—a comparison with Turner syndrome and 46, XX females
MM Nielsen, C Trolle, S Vang… - American Journal of …, 2020 - Wiley Online Library
… In conclusion, we find an overall similar X chromosome … The expression of ncRNAs was
particular abnormal in TS … of an extra X chromosome on the genome-wide DNA methylation and …
particular abnormal in TS … of an extra X chromosome on the genome-wide DNA methylation and …
DNA methylation in satellite repeats disorders
C Francastel, F Magdinier - Essays in Biochemistry, 2019 - portlandpress.com
… of triplet expansion on chromatin structure is indicated. … chromosomal instability includes
the presence of unusual … on the male and female active X chromosome [105,108]. In contrast, …
the presence of unusual … on the male and female active X chromosome [105,108]. In contrast, …
DNA methylation in disease: Immunodeficiency, Centromeric instability, Facial anomalies syndrome
M Vukic, L Daxinger - Essays in biochemistry, 2019 - portlandpress.com
… by abnormal DNA methylation landscapes. The first disorder to be associated with congenital
defects in DNA methylation was … This was only recently revealed in a comprehensive study …
defects in DNA methylation was … This was only recently revealed in a comprehensive study …
Abnormal X chromosome inactivation and tumor development
… the X chromosome is controlled by a single cis-acting total switching … X chromosome, which
prepares to initiate XCI [44]. As Xist RNA expands on the X chromosome, DNA methylation …
prepares to initiate XCI [44]. As Xist RNA expands on the X chromosome, DNA methylation …
X inactivation and escape: epigenetic and structural features
H Fang, CM Disteche, JB Berletch - Frontiers in cell and …, 2019 - frontiersin.org
… modifies chromatin composition and structure of one X chromosome in … Here we focus on X
chromosome inactivation (XCI), a … ) cause a general disruption of DNA methylation patterns at …
chromosome inactivation (XCI), a … ) cause a general disruption of DNA methylation patterns at …
The diverse roles of DNA methylation in mammalian development and disease
MVC Greenberg, D Bourc'his - Nature reviews Molecular cell biology, 2019 - nature.com
… : genes on the inactive X chromosome, imprinted genes and … DNA methylation relies on a
combination of the unusual … 5% of the total number of CGIs, dependent on DNA methylation, …
combination of the unusual … 5% of the total number of CGIs, dependent on DNA methylation, …
X chromosome dosage and the genetic impact across human tissues
M Viuff, A Skakkebæk, EB Johannsen, S Chang… - Genome Medicine, 2023 - Springer
… that the overall … of X chromosome number and sex on the DNA methylation profile, we
performed unsupervised clustering based on all X chromosomal and autosomal CpG methylation …
performed unsupervised clustering based on all X chromosomal and autosomal CpG methylation …
Losing DNA methylation at repetitive elements and breaking bad
XG Pappalardo, V Barra - Epigenetics & chromatin, 2021 - Springer
… both gene expression and chromatin structure. Therefore, … by unscheduled methylation
correlate with abnormal repression … According to the size of the repeated unit and the total length, …
correlate with abnormal repression … According to the size of the repeated unit and the total length, …