Multidrug efflux transporter ABCG2: expression and regulation
… cellular homeostasis and providing tissue protection against … , hence the name breast cancer
resistance protein (BCRP) [18… to cancer, ABCG2 has been observed to be overexpressed …
resistance protein (BCRP) [18… to cancer, ABCG2 has been observed to be overexpressed …
[HTML][HTML] Proteogenomic analysis of enriched HGSOC tumor epithelium identifies prognostic signatures and therapeutic vulnerabilities
NW Bateman, T Abulez, AR Soltis, A McPherson… - NPJ precision …, 2024 - nature.com
… serous ovarian cancer (HGSOC) tissue specimens spanning a … We further identified that
polycomb complex protein BMI-1 is … mutations (tumor protein 53, TP53), breast cancer type 1 and …
polycomb complex protein BMI-1 is … mutations (tumor protein 53, TP53), breast cancer type 1 and …
The regulation of PTEN: Novel insights into functions as cancer biomarkers and therapeutic targets
… of human cancers that overexpress BMI-1 and how BMI-1 … to selected polycomb-group proteins
recruiting polycomb repressive … Osteosarcoma, glioma, cervical cancer Via acting as both …
recruiting polycomb repressive … Osteosarcoma, glioma, cervical cancer Via acting as both …
[HTML][HTML] ALKBH2 inhibition alleviates malignancy in colorectal cancer by regulating BMI1-mediated activation of NF-κB pathway
B Ke, K Ye, S Cheng - World Journal of Surgical Oncology, 2020 - Springer
… site 1 (BMI1) protein is one of the polycomb-group (PcG) family of proteins [14]. Recently, …
important part in tumor development and metastases [15], and BMI-1 overexpression has been …
important part in tumor development and metastases [15], and BMI-1 overexpression has been …
MicroRNA-498 inhibits the proliferation, migration and invasion of gastric cancer through targeting BMI-1 and suppressing AKT pathway
D You, D Wang, P Liu, Y Chu, X Zhang, X Ding, X Li… - Human Cell, 2020 - Springer
… mesenchymal transition (EMT) in endometrial cancer [23]. And … The protein samples were
obtained using RIPA lysis buffer … In this study, we demonstrated that the overexpression of miR-…
obtained using RIPA lysis buffer … In this study, we demonstrated that the overexpression of miR-…
[HTML][HTML] EZH2 regulates oncomiR-200c and EMT markers in esophageal squamous cell carcinomas
F Nourmohammadi, MM Forghanifard… - Scientific Reports, 2022 - nature.com
… Since epigenetics regulatory pathways and polycomb proteins … overexpression and down
regulation of E2F3 and BMI-1 … the promotion of EMT pathway in endometriosis 55 . In gastric …
regulation of E2F3 and BMI-1 … the promotion of EMT pathway in endometriosis 55 . In gastric …
[HTML][HTML] O-GlcNAcylation: an important post-translational modification and a potential therapeutic target for cancer therapy
Q Lu, X Zhang, T Liang, X Bai - Molecular Medicine, 2022 - Springer
… in breast invasive carcinoma (BRCA) and uterine corpus … multiple cancer types (TCGA tumor)
and adjacent normal tissue … O-GlcNAc and cervical cancer, especially in human papilloma …
and adjacent normal tissue … O-GlcNAc and cervical cancer, especially in human papilloma …
Potential role of cancer stem cells as biomarkers and therapeutic targets in cervical cancer
N Sudhalkar, NP Rathod, A Mathews, S Chopra… - Cancer …, 2019 - Wiley Online Library
… polycomb complex protein (also known as polycomb group … and in cancers of the ovary,
prostrate, lung, endometrium, and … DNA damaging agents have an overexpression of Ape1/Ref-1…
prostrate, lung, endometrium, and … DNA damaging agents have an overexpression of Ape1/Ref-1…
[HTML][HTML] BMI1 overexpression is correlated with a poor prognosis and immune infiltration in hepatocellular carcinoma
MC Wang, PT Yang, Y Zhang… - Oncology and Translational …, 2024 - journals.lww.com
… melanoma, and uterine corpus endometrial carcinoma (UCEC) … in HCC tissue compared
with that in normal tissue, which is … Increased polycomb-group oncogene Bmi-1 expression …
with that in normal tissue, which is … Increased polycomb-group oncogene Bmi-1 expression …
CBX8 Together with SET Facilitates Ovarian Carcinoma Growth and Metastasis by Suppressing the Transcription of SUSD2
Y Wu, Y Duan, X Li, R Zhao, B Lan, X Zhang… - Molecular Cancer …, 2022 - AACR
… Polycomb group proteins are often dysregulated in cancer, … lower than that of cervical cancer
and endometrial carcinoma (8)… , when we overexpressed CBX8 in ovarian carcinoma cells (…
and endometrial carcinoma (8)… , when we overexpressed CBX8 in ovarian carcinoma cells (…