Functional interaction among lncRNA HOTAIR and microRNAs in cancer and other human diseases

M Cantile, M Di Bonito, M Tracey De Bellis, G Botti - Cancers, 2021 - mdpi.com
… modifiers, such as the Polycomb repressive complex PRC2 [14,15]. … In endometrial carcinoma,
HOTAIR overexpression has a … arrest by directly suppressing Bmi-1 expression, thereby …

[HTML][HTML] Long non-coding RNA linc00645 promotes TGF-β-induced epithelial–mesenchymal transition by regulating miR-205-3p-ZEB1 axis in glioma

C Li, H Zheng, W Hou, H Bao, J Xiong, W Che… - Cell death & …, 2019 - ncbi.nlm.nih.gov
… between linc00645 overexpression and clinicopathological … been reported in cervical cancer
cells and gastric cancer 37,… level of specific stemness markers, including Bmi-1, Oct-4, Sox-2…

Pharmacoepigenetics of EZH2 Inhibitors

C Lindsay, M Kostiuk, VL Biron - Pharmacoepigenetics, 2019 - Elsevier
… : polycomb-repressive complex 1 (PRC1) and polycomb-… to regulate EZH2 overexpression
in pancreatic cancer, 64 triple… transition of cervical cancer cells both in vitro and in vivo. …

Targeting histone onco-modifications using plant-derived products

SP Illam, SP Kandiyil… - Current Drug Targets, 2021 - ingentaconnect.com
… , and overexpression of Mdm2 causes protein ubiquitination in … nents of the Polycomb
group (PcG) complex; proteins form … Bmi-1 and EZH2 protein levels in SCC 13 skin cancer cell …

Diagnostic and Prognostic Significance of Intracellular Markers of CSCs in Patients with Cancers

K Soha, MA Rahman, F Islam - Cancer Stem Cells: Basic Concept and …, 2023 - Springer
… , overexpression of Msi2 correlated with higher tumor grade … with gastric cancer, HCC, and
cervical cancers. Moreover, … from other cancers such as pancreatic, cervical, and endometrial, …

Diagnostic and Prognostic Significance of Intracellular Markers of CSCs in Patients with Cancers

MAR Kazi Soha, F Islam - Cancer Stem Cells: Basic Concept and Therapeutic … - Springer
overexpression of Msi2 correlated with higher tumor grade and poor prognosis in patients
with gastric cancer, HCC, and cervical cancers… to cancer in type I endometrial carcinomas. Sci …

[HTML][HTML] Chromobox 4 facilitates tumorigenesis of lung adenocarcinoma through the Wnt/β-catenin pathway

Z Wang, Z Fang, G Chen, B Liu, J Xu, F Li, F Li, H Liu… - Neoplasia, 2021 - Elsevier
Polycomb group (PcG) proteins are known as master … stable CBX4-overexpressed cell
models in 2 human LUAD cell … in human LUAD samples at both the mRNA and protein levels, …

[PDF][PDF] A Study of the Regulation of Breast Cancer Cell Invasion

J Lolarga - 2020 - scholarworks.calstate.edu
… usually results in a lump or mass in the breast tissue. Most … overexpression of BMI1 in
several human cancers including … Polycomb-group proteins play a major role in transcriptional …

The effects and mechanisms of epigallocatechin-3-gallate on reversing multidrug resistance in cancer

W Zhang, W Zhang, L Sun, L Xiang, X Lai, Q Li… - Trends in food science & …, 2019 - Elsevier
… suppressed over-expression of heat shock 70 kDa protein (… N-methyltransferase EZH2,
polycomb protein SUZ12, and … of tumor suppressors p16 Ink4a and p19 Arf by Bmi-1 was …

The role of miRNAs in the regulation of endometrial cancer invasiveness and metastasis—a systematic review

K Klicka, TM Grzywa, A Klinke, A Mielniczuk… - Cancers, 2021 - mdpi.com
… virus insertion region-1 (BMI-1), Transcription Factor 3 (E2F3), … EZH2 is the enzymatic catalytic
subunit of the polycomb-… It is overexpressed in many types of cancer, including EC [208], …