Fluoxetine modulates neuronal activity in stress-related limbic areas of adult rats subjected to the chronic social isolation

A Stanisavljević, I Perić, P Gass, D Inta, UE Lang… - Brain research …, 2020 - Elsevier
… Given that Flx showed antidepressant- and anxiolytic- like effects in … different Flx treatment
duration. Moreover, antidepressants play a role in mediating neuroplasticity in brain regions

Neurobiology and Treatment of Sedative-, Hypnotic-, and Anxiolytic-Related Disorders

JL Jones, R Malcolm - The American Psychiatric Association …, 2021 - books.google.com
Chlordiazepoxide was … the unique risks of benzodiazepine use in the elderly, who seemed
to be less sensitive to the therapeutic effects while being more sensitive to the adverse effects, …

[HTML][HTML] Novel pharmacological targets in drug development for the treatment of anxiety and anxiety-related disorders

SB Sartori, N Singewald - Pharmacology & therapeutics, 2019 - Elsevier
… in different phases of clinical trials for their potential in the treatment of fear-, anxiety- and
trauma-related … , which could render chronic anxiolytic drug treatment dispensable for many …

GABAA/benzodiazepine receptors in the dorsal periaqueductal gray mediate the panicolytic but not the anxiolytic effect of alprazolam in rats

AT Frias, GG Fernandes, H Zangrossi Jr - Behavioural Brain Research, 2019 - Elsevier
… that chronic, but not acute treatment with fluoxetine increases … of rats used because of several
overlapping injection sites. dmPAG = … of the benzodiazepine chlordiazepoxide in the social …

Unconventional anxiety pharmacology in zebrafish: Drugs beyond traditional anxiogenic and anxiolytic spectra

MS de Abreu, ACVV Giacomini, KA Demin… - Pharmacology …, 2021 - Elsevier
anxiolytic drugs ethanol, benzodiazepines and fluoxetine (an … In mammals, LSD acts at
different brain regions with a … 5-HT 2C , dopamine D 2 and Trace Amine Associated (eg, TAAR 1 ) …

Design and synthesis of achiral and chiral imidazodiazepine (IMDZ) GABA (A) R subtype selective ligands for the treatment of CNS disorders, as well as Asthma

G Li - 2019 - search.proquest.com
… The binding of ligands at different subunits of GABAA receptors specifically at α1-6β2/3 γ2
anxiolytic activities in mice. This antidepressant effect has been realized with no side effects

Trajectory and magnitude of response in adults with anxiety disorders: a Bayesian hierarchical modeling meta-analysis of selective serotonin reuptake inhibitors …

EM Mendez, JA Mills, V Suresh, JN Stimpfl… - CNS spectrums, 2024 - cambridge.org
fluoxetine OR fluvoxamine OR paroxetine OR sertraline OR vilazodone OR venlafaxine OR
desvenlafaxine OR duloxetine OR alprazolam OR chlordiazepoxide … , overlapping symptoms …

Diazepam effects on anxiety-related defensive behavior of male and female high and low open‐field activity inbred mouse strains

EA Mehrhoff, WC Booher, J Hutchinson… - Physiology & …, 2023 - Elsevier
… -related behavior of these unique strains, using an anxiolytic … these structures are
interconnected and overlapping with … such as chronic administration of imipramine or fluoxetine

The role of brain gaseous neurotransmitters in anxiety

A Pałasz, IC Menezes, JJ Worthington - Pharmacological Reports, 2021 - Springer
… tests, that was notably not different to that evoked by diazepam, (… [73] showed that fluoxetine
downregulates expression of … l-NOARG) abolished anxiolytic activity of chlordiazepoxide [83] …

Neurochemical basis for anxiety and anxiety disorders: evidence from drugs which decrease human fear or anxiety

DE Redmond - Anxiety and the anxiety disorders, 2019 - taylorfrancis.com
… This chapter reviews the biochemical effects of anxiolyticseparate "parallel" systems for
anxiety and for fear/panic; (2) a "congruence" model where overlapping and common effects of …