… dose dependently inhibits recombinant eNOS uncoupling in … hypertrophy, and vascular
structural remodeling in a dose-… GTPCH1 to pathologically relevant concentrations of HOCl (…

… uncoupling phenomenon; proline-rich tyrosine kinase 2 (PYK2), activated by not only oxidative
stress … Indeed, recent evidence has identified that pathological increases in myocardial …

… Oxidative stress drives remodeling of pulmonary arteries and … , oxidative stress causes
pathological lung remodeling in … Il-1β stimulation (1 ng/ml) of primary murine cardiac fibroblasts …

… Shear forces during blood flow stimulate the opening of Ca 2+ … , crucial for vascular
remodeling during pregnancy and injury … However, in pathological conditions, electrons uncouple …

… For example, oxidative stress induced by eNOS uncoupling … results in cardiac remodeling
following a model of myocardial … in both physiological and pathological states of the CVS that …

… oxidative stress for the development of cardiovascular disease, the uncoupling of endothelial
nitric oxide synthase … , it may become detrimental under pathological conditions. We have …

… suggesting common pathological pathways. Mechanistically, … L-NAME-induced hypertension
and cardiac remodelling 76. … and thus initiate eNOS uncoupling that further increases ROS …

… role of nitric oxide/cyclic guanosine 3',5'-monophosphate (NO/cGMP) signalling in cardiac
… mechanisms involved in the pathophysiology of myocardial dysfunction both with reduced (…

… Noise induces inflammation and stimulates several ROS … , all of which indicated cardiac
remodeling and fibrosis. In endothelial … and Alzheimer's disease pathology in rodent studies [45], …

… in hypertrophy due to the lack of uncoupled eNOS has also been seen in … pathological
cardiac hypertrophy [54, 55]. However, the CRS model used here has subtle cardiac remodeling …