… NDA models. Here we start by summarizing evidence from human patients and animal models
to … requires glucose uptake into the brain cells, glycolysis in the cytoplasm and oxidative …

… or protective mechanisms are significantly compromised [30,31]. … in mitochondrial function,
energy metabolism, calcium handling, … and HD animal models [80,81]. Lipid peroxidation is a …

… energy-producing pathways, glycolysis and oxidative … how glial energy metabolism and
axoglial metabolic crosstalk … human samples as well as animal models have long been …

… causing oxidative stress or disruption of metabolism and … In addition to their well-known role
in energy metabolism as the … With less energy available, neuronal function is compromised…

… a deficiency state that compromises cellular growth, function, … susceptible to energy deficit
and oxidative stress. There is an … In animal models of Parkinson’s disease, the injection of …

… of mitochondrial oxidative stress, lipid metabolism, and energy … In light of this
bioenergetics compromise, we might also … and enzymes involved in energy metabolism [138,161,162,163,…

… neuronal cells to maintain a proper energy level can be compromised, thus impacting on Ca
2… been reported in a transgenic AD mouse model that may represent an efficient fatty acid β-…

… proteins are prone to damage by oxidative stress, glycation, … in a mouse model led to decreased
axonal regeneration and … in mitochondria also were compromised with SNPH expression…

… deficiency in neurons, which compromises the capacity to generate … of increased oxidative
stress within the axon judged by … PLP overexpression mouse model, axon degeneration was …

… Compromised brain energy metabolism is a prominent feature in aging and AD … and
oxidative stress have been associated with non-pathological aging in humans and animal models. …