Ferroptosis meets cellcell contacts

C Dietrich, TG Hofmann - Cells, 2021 - mdpi.com
… Oxygenation of ω-6 fatty acids, such as arachidonic acid and its elongation product adrenic
acid, in phosphatidylethanolamines especially seems to be of functional importance for …

The cell biology of ferroptosis

SJ Dixon, JA Olzmann - Nature Reviews Molecular Cell Biology, 2024 - nature.com
… of ferroptosis from mechanisms that regulate ferroptosis sensitivity. The execution of ferroptosis
… of ions across the plasma membrane, cell swelling and plasma membrane rupture 9 . …

Ferroptosis and necroinflammation, a yet poorly explored link

B Proneth, M Conrad - Cell Death & Differentiation, 2019 - nature.com
… of arachidonic (AA; C20:4) and adrenic acid (AdA; C22:4… oxidized during ferroptosis execution
in vivo and exactly these lipid peroxidation signals could be inhibited using the ferroptosis

Lipid metabolism and ferroptosis

JY Lee, WK Kim, KH Bae, SC Lee, EW Lee - Biology, 2021 - mdpi.com
… of how various lipid metabolic pathways are associated with lipid peroxidation and ferroptosis.
Our review will provide insight into treatment strategies for ferroptosis-related diseases. …

[HTML][HTML] Ferroptosis at the intersection of lipid metabolism and cellular signaling

D Liang, AM Minikes, X Jiang - Molecular cell, 2022 - cell.com
… of cellular function and ferroptosis surveillance, and how cellular signaling pathways intersect
with lipid metabolism to regulate ferroptosis, in the contexts of normal biology and disease. …

Oxidative damage and antioxidant defense in ferroptosis

F Kuang, J Liu, D Tang, R Kang - … in cell and developmental biology, 2020 - frontiersin.org
oxidative and antioxidant systems, acting together autophagy machinery, shape the process
of lipid peroxidation during ferroptosis… 4 ) system limits oxidative damage during ferroptosis. …

Ferroptosis: machinery and regulation

X Chen, J Li, R Kang, DJ Klionsky, D Tang - Autophagy, 2021 - Taylor & Francis
… of oxidative cell death caused by glutamate toxicity [Citation17]. The inhibition of ferroptosis
and … infection responses by ferroptotic immune cells (eg, T and B cells), ferroptosis-mediated …

Achieving life through death: redox biology of lipid peroxidation in ferroptosis

H Bayır, TS Anthonymuthu, YY Tyurina, SJ Patel… - Cell chemical …, 2020 - cell.com
… According to one school of thought, ferroptotic death is a penalty imposed on a particular
cell within a multicellular community that exhibits severe and irreparable, dis-coordinated …

Dynamic regulation of ferroptosis by lipid metabolism

N Naowarojna, TW Wu, Z Pan, M Li… - Antioxidants & Redox …, 2023 - liebertpub.com
… prevent and repair membrane lipid damage under ferroptotic conditions. Future Directions:
Cell … abundant levels of oxidized PEs containing arachidonic acid or adrenic acid at the sn-2 …

Ferroptosis

D Tang, G Kroemer - Current Biology, 2020 - cell.com
… , hypoxia, and radiation) induce ferroptotic cell death. The abnormal … and regulation of
ferroptosis in mammalian cells, as well as … arachidonic acid and adrenic acid) promote ferroptosis, …