… unique nanoplatform in effective SDT by generating sufficient ROS in deep-seated hypoxic
tumors … the efficient tumor oxygenation and hypoxia relief by hypoxia-responsive ALA-hMVs. …

… also for reducing drug resistance to enhance therapeutic efficacy. … We believe that our
oxygen-sufficient nanoplatform could be … Thus, PPID-NPs hold high promise for alleviating hypoxic …

… successfully makes the net level of ROS rise more via breaking … 2 release for removing
hypoxia-induced resistance to radiotherapy … Various hypoxic TME engineered nanoplatforms for …

… could overcome hypoxia-associated RT-resistance of tumor … nanomaterials to thoroughly
relieve the hypoxia because they … Thereby, the nanoplatform reduced invasion and metastasis …

… far-reaching influence on the resistance to diverse oxygen-… by PGI NPs could potentially
relieve tumor hypoxia to increase the … Collectively, this study presented a robust nanoplatform for …

… sonodynamic therapy (SDT) via the conversion of oxygen into cytotoxic reactive oxygen species
(ROS) but also aggravated hypoxia … an intelligent MOF-based nanoplatform (denoted as …

… been devoted to overcoming hypoxia-relevant therapeutic resistance, including tumor-…
hypoxia-irrelevant mechanism was different from the conventional strategies of relieving hypoxia, …

… resistance by relieving tumor hypoxia but also increase ROS production for enhanced
sonodynamic … The nanoplatform we developed includes two distinct features: (i) conjugated …

… resistance. Among all the new therapeutic strategies developed to resolve drug resistance
… Meanwhile, hypoxia is another inherent phenomenon that affects the treatment efficiency of …

… of sonodynamic therapy (SDT) is largely dependent upon oxygen availability to generate
deleterious reactive oxygen species, and as such, hypoxic … such that they break down when …