Multifunctional sonosensitizers in sonodynamic cancer therapy

S Son, JH Kim, X Wang, C Zhang, SA Yoon… - Chemical Society …, 2020 - pubs.rsc.org
oxygen-self-produced nanoplatformnanoplatforms in breaking hypoxia-specific transport
barriers, releasing oxygen and modulating hypoxia, diminishing hypoxia-induced resistance to …

Hypoxia-adapted sono-chemodynamic treatment of orthotopic pancreatic carcinoma using copper metal–organic frameworks loaded with an ultrasound-induced free …

Y Sun, J Cao, X Wang, C Zhang, J Luo… - … Applied Materials & …, 2021 - ACS Publications
… of sonodynamic therapy (SDT) is largely dependent upon oxygen availability to generate
deleterious reactive oxygen species, and as such, hypoxic … such that they break down when …

Oncolytic impediment/promotion balance disruption by sonosensitizer-free nanoplatforms unfreezes autophagy-induced resistance to sonocatalytic therapy

L Lu, T Wang, C Fang, L Song, C Qian… - … Applied Materials & …, 2022 - ACS Publications
nanoplatform (SFTON) consisting of chloroquine (CQ) and porphyrin-structured metal centers
(PMCS) was engineered to break … methods such as multiresistance, hypoxia, inflammation, …

Research progress on tumor hypoxia-associative nanomedicine

XX Xu, SY Chen, NB Yi, X Li, SL Chen, Z Lei… - Journal of Controlled …, 2022 - Elsevier
… , photodynamic therapy, sonodynamic therapy and … fit the hypoxic environment, enhances
cancer cell resistance, then … This nanoplatform combined with antiprogrammed death-ligand 1 …

Two-Dimensional MXene-Originated In Situ Nanosonosensitizer Generation for Augmented and Synergistic Sonodynamic Tumor Nanotherapy

M Zhang, D Yang, C Dong, H Huang, G Feng, Q Chen… - ACS …, 2022 - ACS Publications
… of H 2 O 2 , acidic pH, redox conditions, specific enzymes, hypoxia, etc.) to construct TME-responsive
cancer-therapeutic nanoplatforms has become a hot spot in recent years. (3−6) A …

Hypoxia-alleviated sonodynamic therapy based on a hybrid protein oxygen carrier to enhance tumor inhibition

T Yin, J Yin, H Ran, Y Ren, C Lu, L Liu, Q Shi… - Biomaterials …, 2022 - pubs.rsc.org
… The –S–S– bonds in HSA are first broken by GSH, and then Hb and MnPcS are added to …
in the MnPcS@HPO group indicated the hypoxia relief due to the effective O 2 afforded from …

Nanoparticles-mediated reoxygenation strategy relieves tumor hypoxia for enhanced cancer therapy

H Wang, J Li, Y Wang, X Gong, X Xu, J Wang… - Journal of Controlled …, 2020 - Elsevier
… , photodynamic therapy (PDT), sonodynamic therapy (SDT) and … fluorinated nanoplatform
effectively circumvented hypoxia-… by conquering the hypoxia-involved therapeutic resistance. …

[HTML][HTML] Modulation of reactive oxygen species to enhance sonodynamic therapy

X Liu, X Pan, C Wang, H Liu - Particuology, 2023 - Elsevier
… -PpIX-LA-CO 2 nanoplatform to enhance ROS production for … and release O 2 to improve
hypoxia at the tumor site. Fluorescence … Hypoxia immunofluorescence detection of tumor slices …

[HTML][HTML] Albumin-based smart nanoplatform for ultrasound-mediated enhanced chemo‐sonodynamic combination therapy

DG Zhang, BQ Chen, YJ Pan, H Liu, YH Shi, LF Chen… - Materials & Design, 2023 - Elsevier
hypoxic microenvironment increases the tumor resistance to SDT, hindering its therapeutic
efficacy. In this work, an ingenious nanoplatform … reduced hypoxia-mediated SDT resistance

[HTML][HTML] Nanomedicine-based strategies assisting photodynamic therapy for hypoxic tumors: state-of-the-art approaches and emerging trends

CY Shih, PT Wang, WC Su, H Teng, WL Huang - Biomedicines, 2021 - mdpi.com
… -/radio-resistance [9,10]. Moreover, via the up-regulated, … CaO 2 has been used for oxygen
generating to relieve hypoxia … methods with a single nanoplatform can ensure effective co-…