… , ROS-generating systems that can conquer SDT resistance induced by hypoxia [30]. …
ROS in a sonodynamic therapy via interaction with ultrasound irradiation to break their bridging …

… improving hypoxia to increase the efficacy of sonodynamic … thus making tumors more
resistant to many current treatments… -chain-media oxygen-self-produced nanoplatform (IR780@O …

… chemo-sonodynamic therapy against pancreatic cancer. It is demonstrated that the PO/GI-MCs
could reverse the hypoxic … for enhancing chemo-sonodynamic therapy for hypoxic tumors. …

… hypoxic microenvironment and promotes tumor metastasis and recurrence. Therefore, we
propose a novel sonodynamic … Therefore, anti-PD-L1 with relieving immunosuppression in …

… capable of greatly relieving tumor hypoxia through catalyzing the decomposition of H2O2 in
situ. Oxygen re-generation not only prevented hypoxia-mediated chemo-resistance, but also …

… , our nanoplatform displayed extraordinary sonodynamic therapeutic effect with low …
Encouraged by the excellent effect of HA-MON@Ce6/CAT in alleviating tumor hypoxia, we next …

… and mechanism of these nanoplatforms. Future challenges … metastasis but also enhances
tumor resistance to the ROS-… therapy (CDT), and sonodynamic therapy (SDT), thus leading to …

… Hypoxia is thus a major cause of resistance to RT. An adequate O 2 supply is indeed critical
… 2 in hypoxic tumors critically hampers PDT by limiting critical ROS generation. Sonodynamic …

… , radiotherapy, photodynamic therapy, sonodynamic therapy and immunotherapy are negatively
affected … In conclusion, hypoxia highly contributes to multi-drug resistance of the cancer. …

… have been devoted to alleviating hypoxia, such as directly … , the research on MnO 2 -based
nanoplatforms in SDT is still at the … , we designed an intelligent nanoplatform based on MnO 2 …