Oxytocin, a novel treatment for methamphetamine use disorder

AN Edinoff, E Thompson, CE Merriman… - Neurology …, 2022 - mdpi.com
… of oxytocin on methamphetamine-induced hyperactivity on … oxytocin administration [51].
This could be a reason why there was a decrease in the self-administration of methamphetamine

The effect of chronic oxytocin treatment during abstinence from methamphetamine self-administration on incubation of craving, reinstatement, and anxiety

NA Everett, SJ Baracz, JL Cornish - Neuropsychopharmacology, 2020 - nature.com
… For example, rats treated for 10 days with oxytocin during adolescence exhibited reduced
substantially higher locomotor hyperactivity during self-administration than LgA males despite …

The vagus nerve mediates the suppressing effects of peripherally administered oxytocin on methamphetamine self-administration and seeking in rats

NA Everett, AJ Turner, PA Costa, SJ Baracz… - …, 2021 - nature.com
… Further, as preclinical evidence suggests that female rats display higher METH intake and
reinstatement [44], and as the efficacy of oxytocin for reducing METH self-administration and …

Effect of social housing and oxytocin on the motivation to self-administer methamphetamine in female rats

C Westenbroek, AN Perry, L Jagannathan… - Physiology & …, 2019 - Elsevier
reduce METH and cue-induced reinstatement of drug taking. Finally, we assessed whether
OT, after long-term METH self-administration, would reduce … METH self-administration found …

Berberine hydrochloride attenuates voluntary methamphetamine consumption and anxiety-like behaviors via modulation of oxytocin receptors in methamphetamine …

MM Alavijeh, G Vaezi, M Khaksari, V Hojati - Physiology & behavior, 2019 - Elsevier
oxytocin receptor in the hippocampus. It represents that the oxytocin receptor decreases in
the methamphetamine-… The percentage of oxytocin receptor in the hippocampus increased in …

Effect of systemically administered oxytocin on dose response for methylphenidate selfadministration and mesolimbic dopamine levels

MR Lee, MCH Rohn, C Zanettini… - Annals of the New …, 2019 - Wiley Online Library
… of MP on attention deficit hyperactivity disorder symptoms is … mg/kg), reduced SA and
reinstatement of methamphetamine-… changes: a reduction in methamphetamine-induced c-Fos …

The modulation of methamphetamine-induced behaviours by oxytocin in the nucleus accumbens core and subthalamic nucleus

SJ Baracz - 2022 - figshare.mq.edu.au
… following chronic methamphetamine self-administration … core of the rat reduces
methamphetamine reinstatement. Sydney … STh in addition to METH hyperactivity. Such findings …

Repeated oxytocin treatment during abstinence inhibited context-or restraint stress-induced reinstatement of methamphetamine-conditioned place preference and …

J Cai, X Che, T Xu, Y Luo, M Yin, X Lu, C Wu… - Experimental …, 2022 - Elsevier
… Propensity to relapse, even after long-term abstinence, is a crucial feature of methamphetamine
(METH) abuse. We and other laboratories have reported that acute treatment of oxytocin

The interaction of oxytocin and vasopressin systems in reducing relapse to methamphetamine abuse

NA Everett - 2022 - figshare.mq.edu.au
… systemic administration of OXY to reduce METH-seeking behaviour is … The intravenous drug
self-administration model of … show some ability to reduce anxiety, hyperactivity, and general …

Oxytocin treatment in the prelimbic cortex reduces relapse to methamphetamine-seeking and is associated with reduced activity in the rostral nucleus accumbens core

N Everett, S Baracz, J Cornish - Pharmacology Biochemistry and Behavior, 2019 - Elsevier
… tonic GABA activity in the PrL reduces METH-hyperactivity (unpublished). Furthermore,
our … OXY reduces METH-hyperactivity primarily in rats with a history of METH self-administration, …