Oxytocin treatment for alcoholism: Potential neurocircuitry targets
… tegmental area (VTA) to nucleus accumbens (NAc) to signal … potential of OT treatment for
alcohol use disorder (AUD) by … evidence indicating OT inhibits motivation for ethanol reward, …
alcohol use disorder (AUD) by … evidence indicating OT inhibits motivation for ethanol reward, …
[HTML][HTML] Oxytocin blocks enhanced motivation for alcohol in alcohol dependence and blocks alcohol effects on GABAergic transmission in the central amygdala
… nucleus of the amygdala (CeA; a key brain region in the network of dysregulations induced
by alcohol dependence) indicated that oxytocin … effects of oxytocin, including inhibition of …
by alcohol dependence) indicated that oxytocin … effects of oxytocin, including inhibition of …
Alcohol and oxytocin: scrutinizing the relationship
AE Ryabinin, HD Fulenwider - Neuroscience & Biobehavioral Reviews, 2021 - Elsevier
… Alcohol inhibits oxytocin release from hypophyseal terminals in males and females. …
accompanied by increased OXTR mRNA levels in several cortical areas, nucleus accumbens (NAC), …
accompanied by increased OXTR mRNA levels in several cortical areas, nucleus accumbens (NAC), …
Environmental enrichment enhances ethanol preference over social reward in male swiss mice: Involvement of oxytocin-dopamine interactions
… levels in the nucleus accumbens (A) Levels of D 1 receptors in the NAc of CT and EE groups
(n = 7–8/group) (B) Levels … to amphetamine inhibits the formation of mating-induced partner …
(n = 7–8/group) (B) Levels … to amphetamine inhibits the formation of mating-induced partner …
Oxytocin reverses ethanol consumption and neuroinflammation induced by social defeat in male mice
MD Reguilón, C Ferrer-Pérez, J Miñarro… - Hormones and …, 2021 - Elsevier
… There are no studies evaluating the potential effect of OXT on the increased consumption
of EtOH induced by social defeat. However, we know that mice treated with OXT prior to each …
of EtOH induced by social defeat. However, we know that mice treated with OXT prior to each …
The role of oxytocin in alcohol and drug abuse
… reduced alcohol-induced CPP and alcohol consumption in … Moreover, alcohol-induced
elevation of dopamine release … ), and this inhibition was associated with a reduction in alcohol …
elevation of dopamine release … ), and this inhibition was associated with a reduction in alcohol …
Activation of hypothalamic oxytocin neurons reduces binge-like alcohol drinking through signaling at central oxytocin receptors
CE King, WC Griffin, MF Lopez… - …, 2021 - nature.com
… containing neurons in the paraventricular nucleus of the hypothalamus (PVN) alters alcohol
… mechanism whereby exogenous OT stimulates hypothalamic release of endogenous OT [24,…
… mechanism whereby exogenous OT stimulates hypothalamic release of endogenous OT [24,…
Systemic oxytocin administration alters mesolimbic dopamine release in mice
… transmission in areas associated with anxiety and addiction, the amygdala and the nucleus
… NAc but not amygdala dopaminergic response to a DAT inhibitor. These regional variations …
… NAc but not amygdala dopaminergic response to a DAT inhibitor. These regional variations …
[HTML][HTML] Oxytocin and addiction: potential glutamatergic mechanisms
… in the paraventricular nucleus (PVN) and supraoptic nucleus (SON) … show that alcohol can
inhibit presynaptic Glu release and … found Glu levels to increase after alcohol administration, …
inhibit presynaptic Glu release and … found Glu levels to increase after alcohol administration, …
The potential role of oxytocin in addiction: What is the target process?
F Sanna, MA De Luca - Current Opinion in Pharmacology, 2021 - Elsevier
… bed nucleus of the stria terminalis as a key structure where … of Ethanol-induced dopamine
release and reduced EtOH self… for the ability of oxytocin to inhibit ethanol-induced negative …
release and reduced EtOH self… for the ability of oxytocin to inhibit ethanol-induced negative …