… Rather, evidence for the use of imaging as a biomarker, for … , neuroimaging biomarkers are
best established clinically for … guide future clinical trials to improve medical decision making…

… lesions who may need imaging. This review provides a contemporary clinical and laboratory
framework for blood biomarker … diagnosis of mTBI and this biomarker is now widely used in …

… mild traumatic brain injury (MTBI), 1 and intracranial injuries … (CT) scan of the brain is the
diagnostic standard for acute … ability of the biomarkers to detect intracranial lesions on CT scan. …

… concerning the utility of both imaging and blood biomarkers. … of clinical trials. The two largest
studies assessing outcome … utility in the use of biomarkers for outcome prediction.31 32 In …

… dealt with the use of the same biomarkers to predict the same … objective information to
inform clinical trials for both mechanism … the need for a CT scan after mTBI, predicting delayed …

… diagnostic performance of GFAP versus S100B in predicting … biomarkers for predicting
intracranial injury on head CT scan … (ALERT-TBI) trial for patients who present with a GCS of 13–…

… and compare the diagnostic performance of a panel of 6 biomarkers reflecting distinct types
of … of biomarkers for predicting abnormalities on MR imaging performed within 3 weeks of …

… the diagnostic and predictive value of circulating biomarkers … of the clinical trial, 243 patients
with complete biomarker and … radiologic findings on CT scan, long-term neurologic outcome…

… in a new set of protein biomarkers as diagnostic and prognostic aids in TBI. … imaging and
biomarker levels were available, we explored whether biomarker levels at ∼8 months predicted …

… scan and/or clinical course suggested presence of diffuse axonal injury (DAI), magnetic
resonance imaging … represent a valuable tool for improved patient stratification in future TBI trials. …