Regulation of the complement system by pentraxins

K Haapasalo, S Meri - Frontiers in immunology, 2019 - frontiersin.org
… SAP), and pentraxin-3 (PTX3) belong to the pentraxin family of … The listed three members
have been shown to interact with … interactions between pentraxins and the complement system, …

The long pentraxin PTX3 as a link between innate immunity, tissue remodeling, and cancer

A Doni, M Stravalaci, A Inforzato, E Magrini… - Frontiers in …, 2019 - frontiersin.org
Pentraxins and components of the complement system also interact with elements present …
additional regulatory roles of the innate immune system in the tissue response to injury (53, 59…

The long pentraxin PTX3 as a humoral innate immunity functional player and biomarker of infections and sepsis

R Porte, S Davoudian, F Asgari, R Parente… - Frontiers in …, 2019 - frontiersin.org
… on the complement system, since PTX3 enhances … pathway of the complement cascade,
leading to C3 deposition on apoptotic cells (32). In contrast, the interaction between PTX3

Control of complement activation by the long pentraxin PTX3: implications in age-related macular degeneration

M Stravalaci, F Davi, R Parente, M Gobbi… - Frontiers in …, 2020 - frontiersin.org
… A close crosstalk between the long pentraxin PTX3 and the complement system has been
… To our knowledge, this is the first report of a direct interaction between PTX3 and C3b. …

Long Pentraxins and Cancer: A Complex Role Between Immunity and Inflammation

V Catalano, F Spadaccino, M Gigante, GS Netti… - Handbook of Cancer …, 2023 - Springer
Pentraxin 3 (PTX3), the prototype of long pentraxins, plays a … , PTX3 has the ability to influence
the complement system (CS… interaction with some key factors of the complement cascade

Structural insights into the biological functions of the long pentraxin PTX3

AM Massimino, FE Colella, B Bottazzi… - Frontiers in …, 2023 - frontiersin.org
… , PTX3 cross talks to components of the complement system to … ‘90s, PTX3 is considered the
paradigm of long pentraxins (27). … , this long pentraxin is known to interact with complement

[HTML][HTML] Perspectives on long pentraxin 3 and rheumatoid arthritis: several potential breakthrough points relying on study foundation of the past

C Qiu, Y Han, H Zhang, T Liu, H Hou… - … Journal of Medical …, 2021 - ncbi.nlm.nih.gov
… This review infers the insight into the interaction of PTX3 in RA and aims to provide novel …
Pentraxins and complement system can opsonize apoptotic cells, promptly facilitating the …

The complement system in Aspergillus fumigatus infections and its crosstalk with pentraxins

R Parente, A Doni, B Bottazzi, C Garlanda… - FEBS …, 2020 - Wiley Online Library
… to the long pentraxin PTX3 as a nonredundant and complement-… , thus standing as a paradigm
of the interplay between … not recognized by PTX3), and no direct interaction of PTX3 with …

[图书][B] The long pentraxin PTX3 as a functional ancestor of antibodies in the immune response to aspergillus fumigatus

R Parente - 2019 - search.proquest.com
… A key role in the early immune response to AF is played by the complement system, an …
fumigatus, and in general of any invading microbe, by a mammalian host involves the interaction

Pentraxin 3 in cardiovascular disease

G Ristagno, F Fumagalli, B Bottazzi… - Frontiers in …, 2019 - frontiersin.org
… key properties of PTX3 as prototypic member of the pentraxin superfamily in … interaction of
PTX3 with Factor H (FH), the most important regulator of the alternative complement pathway, …