The secret garden of neuronal circRNAs
… layer of neuronal gene expression regulation, with known and … through a very specific
pathway based on an almost perfect … Interestingly, we found various low free-energy interactions …
pathway based on an almost perfect … Interestingly, we found various low free-energy interactions …
Multi-OMICS approaches in cancer biology: New era in cancer therapy
S Chakraborty, G Sharma, S Karmakar… - Biochimica et Biophysica …, 2024 - Elsevier
… Modelling these interactions as a regulatory network reveals … The identified molecular
fragments found during data capture … classification and survival analysis of acute myeloid …
fragments found during data capture … classification and survival analysis of acute myeloid …
Uncovering cancer vulnerabilities by machine learning prediction of synthetic lethality
S Benfatto, Ö Serçin, FR Dejure, A Abdollahi… - Molecular Cancer, 2021 - Springer
… of the model, and (ii) all-relevant methods, that find all the … (Functional Analysis through
Hidden Markov Models) predictions [22], … and are involved in cell cycle regulation. In the case of …
Hidden Markov Models) predictions [22], … and are involved in cell cycle regulation. In the case of …
Systems Biology for Engineering Regenerative Immunotherapies in Precision Neuro-Oncology
DD Monie - 2021 - search.proquest.com
… Pathway-based classifications will facilitate matching … EGFRvIII CAR-T cells as a model, we
found that OV-derived type I … The CERES computational model is applied to decouple gene …
found that OV-derived type I … The CERES computational model is applied to decouple gene …
Using biological and chemical information to improve understanding of drug mechanism of action on the systems-level
L Hosseini-Gerami - 2022 - repository.cam.ac.uk
… such as cancer, pathway-based drug repurposing has enabled the … Transcription factor-gene
regulatory networks can be … a signal through the network via the hidden layers, which are …
regulatory networks can be … a signal through the network via the hidden layers, which are …
SARS-CoV-2: Understanding the transcriptional regulation of ACE2 and TMPRSS2 and the role of single nucleotide polymorphism (SNP) at codon 72 of p53 in the …
… acute lymphocytic leukemia (ALL) [71,72,73]. As the transcription factor human tumor suppressor
gene … inhibitors on COVID-19 patients, though we may we find better outcomes as well. …
gene … inhibitors on COVID-19 patients, though we may we find better outcomes as well. …
Systems biology and integrated computational methods for cancer-associated mutation analysis
A Zia, S Rashid - … of Cancer Genomic, Computational Approaches and …, 2020 - Springer
… make a network model, for example, metabolic, regulatory, … Detailed analysis based on gene
networks has been applied … on Hidden Markov model, known as FATHMM, helps in finding …
networks has been applied … on Hidden Markov model, known as FATHMM, helps in finding …
Step by step: towards a better understanding of the genetic architecture of Alzheimer's disease
JC Lambert, A Ramirez, B Grenier-Boley… - Molecular …, 2023 - nature.com
… E (APOE) gene was found to be associated with a 3- to 4-fold … Similarly, differential regulation
of APOE expression related … Heterogeneous or even hidden genetic signals (eg those that …
of APOE expression related … Heterogeneous or even hidden genetic signals (eg those that …
[图书][B] Cheminformatics and bioinformatics at the interface with systems biology: bridging chemistry and medicine
… computational tools is a severe shortcoming for postgraduate … software tools to elucidate
hidden or complex biological data. … networks includes bistability and oscillations, and regulatory …
hidden or complex biological data. … networks includes bistability and oscillations, and regulatory …
13 Systems Biology and Integrated Computational Methods for Cancer-Associated Mutation Analysis
A Zia, S Rashid - 'Essentials of Cancer Genomic, Computational …, 2020 - books.google.com
… make a network model, for example, metabolic, regulatory, and signaling … based on Hidden
Markov model-based tool for functional analysis of … Network or pathway-based approaches …
Markov model-based tool for functional analysis of … Network or pathway-based approaches …