Objective: Lp(a) (lipoprotein[a]) concentrations are associated with atherosclerotic cardiovascular
disease (ASCVD), and new therapies that enable potent and specific reduction are in …

Autoimmune diseases, such as Systemic Lupus Erythematosus (SLE) or Rheumatoid
Arthritis (RA) are characterized by the breakdown of immunological tolerance. Defects of …

The Glial cell line-derived neurotrophic Family Ligands (GFL) are soluble neurotrophic factors
that are required for development of multiple human tissues, but which are also important …

… Such new insights have significant implications for the plasticity of the bone marrow to …
Understanding these changes may help to diagnose and treat inflammatory diseases more …

… Pathologic cells, including cancer cells, secrete specific EVs with different compositions;
therefore, EV can be used as diagnostic tools for certain diseases and can also be monitoring …

… disease is characterized by an extensive secretion of immunoglobulins, accompanied by
structural bone defects and kidney damage … proposed as a new target in the treatment of HD. …

… diseases and vitamin K deficiency, fully revealed its importance. [ Citation 2–12 ] Thus now
this protector of our blood, bones, kidney and brain is deemed essential to human health. …

… drive the pathogenesis of renal disorders. In this Review, we discuss the latest insights into
the … In fact, enthusiasts have suggested that the field of ‘precision medicine’, which is currently …

… Additional cystic kidney diseases not associated with kidney renal enlargement, such as
those caused by mutations in DNAJB11 or ALG9, should be considered ( 24 , 37 ). ADTKD …

… the early stages, most patients with CKD advance to the stage of renal failure at the time of
… biomarkers to diagnose CKD, providing new insights into the association between CKD and …