[HTML][HTML] Long non-coding RNAs: from disease code to drug role

Y Chen, Z Li, X Chen, S Zhang - Acta Pharmaceutica Sinica B, 2021 - Elsevier
new insights into the diagnosis and treatment of diseases. … of chronic kidney disease and
end-stage renal disease 33 , … , symbolizing a new direction for precision medicine 132 , 133 . …

Genetic testing in steroid-resistant nephrotic syndrome: why, who, when and how?

R Preston, HM Stuart, R Lennon - Pediatric nephrology, 2019 - Springer
kidney disease in childhood and has a significant risk of rapid progression to end-stage renal
disease. … disease and provide new insights into podocyte biology and glomerular function. …

L-carnitine and acylcarnitines: mitochondrial biomarkers for precision medicine

MR McCann, MV George De la Rosa, GR Rosania… - Metabolites, 2021 - mdpi.com
… bring new insights into the metabolic mechanisms that underlie certain diseases and ADRs.
… occasion, arrhythmias, heart failure, renal insufficiency, hepatomegaly, and rhabdomyolysis …

[HTML][HTML] Molecular mechanisms and therapeutic targets for diabetic kidney disease

KR Tuttle, R Agarwal, CE Alpers, GL Bakris… - Kidney international, 2022 - Elsevier
disease mechanisms to slow progression to kidney failure … association studies have yielded
new insights that shed light on … under investigation in the Kidney Precision Medicine Project, …

Promising applications of tumor spheroids and organoids for personalized medicine

Z Gilazieva, A Ponomarev, C Rutland, A Rizvanov… - Cancers, 2020 - mdpi.com
… to prescribe an effective treatment [2]. The development of personalized medicine includes
methods of preventing, diagnosing and treating a pathological condition based on the patient’…

Long non-coding RNAs towards precision medicine in gastric cancer: early diagnosis, treatment, and drug resistance

L Yuan, ZY Xu, SM Ruan, S Mo, JJ Qin, XD Cheng - Molecular cancer, 2020 - Springer
… in the early diagnosis, treatment, prognosis, and drug resistance of gastric cancer may …
new insights for precise treatment and individualized management of patients with this disease

African genetic diversity and adaptation inform a precision medicine agenda

L Pereira, L Mutesa, P Tindana, M Ramsay - Nature Reviews Genetics, 2021 - nature.com
… in many human populations, with important consequences for disease susceptibility. We
believe that precision medicine approaches have transformative potential based on a clear …

[HTML][HTML] Thrombotic thrombocytopenic purpura: toward targeted therapy and precision medicine

P Coppo, A Cuker, JN George - Research and practice in thrombosis and …, 2019 - Elsevier
… caplacizumab as a new standard of care for all iTTP patients from diagnosis? Such a
strategy would be expected to facilitate faster platelet count and organ damage recovery and …

Prospects and clinical perspectives of total-body PET imaging using plastic scintillators

P Moskal, E Stępień - PET clinics, 2020 - pet.theclinics.com
… Imaging with such a large AFOV would open new perspective for diagnosis of diseases
affecting the body and brain simultaneously. J-PET may be constructed as a modular, light and …

Atherosclerosis in chronic kidney disease: more, less, or just different?

JM Valdivielso, D Rodríguez-Puyol… - … , and vascular biology, 2019 - Am Heart Assoc
… These insights may help design future clinical trials of stratified personalized medicine
Proinflammatory changes in patients with advanced renal disease include increased …