… existing CYP3A5 test results for initial dosing of tacrolimus. … CYP3A5 genotype to phenotype
interpretation and clinical … as rejection, CNI-induced nephrotoxicity, and BK polyomavirus …

… , and CYP3A5*3 genotype were identified as significant … -kg patient with CYP3A5*3/*3 receiving
a daily tacrolimus dose of 3 … a theoretical basis for personalized tacrolimus treatment and …

… Tac dosing equations including common genotypes for … of kidney allograft recipients and a
custom SNP array, we found … This study identified genetic variants in CYP3A4, CYP3A5, POR …

… , genotype testing could also be used to predict the dosage of … For instance, complicating
toxicity induced by irinotecan has … that has proved effective for personalized medicine, was …

… The personalized C0 was then calculated using the cross-… could not show an effect of
CYP3A5 expression on AUC/C0 … *22 genotype as all patients were homozygous CC carriers. …

… Step I: the TPM of CYP3A4 and CYP3A5, and SNPs genotypes … to be the stable maintenance
tacrolimus dose. Log-transformed … and personalize usage of CYP3A-related drugs such as …

… demonstrated that CYP3A5 genotype-based tacrolimus dosing led … , a personalized
tacrolimus starting dose may be … by CYP3A5 genotype for induction and maintenance phases of …

… that donor CYP3A5 expression significantly decreased tacrolimus dose-… CYP3A5 genotyping
both in recipients and donors was necessary to establish a personalized tacrolimus dosage …

… correlates with the tacrolimus dose requirement after organ … donor CYP3A5 genotypes, we
divided the genotypes into … to induce cytochrome P450 [50], and there were dose differences …

… Acute rejection and tacrolimus-induced toxicity seem to have … BW alone, whereas maintenance
dose algorithms could also … All four identified popPK models include CYP3A5 genotype …