Polymorphisms associated with fentanyl pharmacokinetics, pharmacodynamics and adverse effects
M Saiz‐Rodríguez, D Ochoa, C Herrador… - Basic & clinical …, 2019 - Wiley Online Library
… In order to study whether pharmacogenetics explains some of … between the pharmacokinetic
parameters of fentanyl and BP, HR and QTc. Regarding differences between sexes, women …
parameters of fentanyl and BP, HR and QTc. Regarding differences between sexes, women …
Sex differences in adverse drug reactions: Are women more impacted?
C Lacroix, A Maurier, B Largeau, A Destere… - Therapies, 2023 - Elsevier
… sex differences appear also in the field of pharmacogenomics. … 8 of the 10 biological research
areas, there was a male bias in … behaviors of ADRs may differ between men and women. …
areas, there was a male bias in … behaviors of ADRs may differ between men and women. …
The effect of gender and ABCB1 gene polymorphism on the pharmacokinetics of azithromycin in healthy male and female Pakistani subjects
S Nazir, K Adnan, R Gul, G Ali… - Canadian Journal of …, 2020 - cdnsciencepub.com
… The Student t test was applied to compare pharmacokinetic parameters of azithromycin
between male and female … A significant difference was observed in pharmacokinetic parameters …
between male and female … A significant difference was observed in pharmacokinetic parameters …
Sex differences in pharmacokinetics
I Zucker, BJ Prendergast - Sex and Gender Effects in Pharmacology, 2023 - Springer
… to determine how biological sex and body weight interact to … Some reports with claims of no
statistical differences between … the strong association between elevated PKs in women and …
statistical differences between … the strong association between elevated PKs in women and …
Men and women respond differently to antipsychotic drugs
MV Seeman - Neuropharmacology, 2020 - Elsevier
… Different AP differ in these properties but they all interact with … both pharmacokinetic and
pharmacodynamic sex differences in … differences between men and women. However, younger …
pharmacodynamic sex differences in … differences between men and women. However, younger …
The impact of pharmacogenomics in personalized medicine
DB Singh - Current Applications of Pharmaceutical Biotechnology, 2020 - Springer
… difference between the level of different hormones between … of testing and Pharmacogenomics
data, pharmacokinetics and … of drug, drug history, and drug-drug interactions. Service …
data, pharmacokinetics and … of drug, drug history, and drug-drug interactions. Service …
Common UGT1A6 Variant Alleles Determine Acetaminophen Pharmacokinetics in Man
MO Cerezo-Arias, J Gómez-Tabales, M Martí… - Journal of Personalized …, 2022 - mdpi.com
… interaction was identified in this study. We conclude that sex and UGT1A6 variants determine
… pharmacokinetics, thus providing evidence to eventually developing pharmacogenomics …
… pharmacokinetics, thus providing evidence to eventually developing pharmacogenomics …
Pharmacogenomics and warfarin therapy
JH Martin - Therapeutic Drug Monitoring, 2024 - Elsevier
… contribute to pharmacokinetics and pharmacodynamics of warfarin … diet, ethnicity, drug
interactions, and the pharmacogenetic … Although pharmacogenomics testing per se is an exciting …
interactions, and the pharmacogenetic … Although pharmacogenomics testing per se is an exciting …
Genophenotypic factors and pharmacogenomics in adverse drug reactions
R Cacabelos, V Naidoo, L Corzo, N Cacabelos… - International journal of …, 2021 - mdpi.com
… category, route of administration, and drug–drug interactions. … % of drugs with female-biased
pharmacokinetic values were … Well-established differences among ethnic groups in drug …
pharmacokinetic values were … Well-established differences among ethnic groups in drug …
Influence of germline genetics on tacrolimus pharmacokinetics and pharmacodynamics in allogeneic hematopoietic stem cell transplant patients
J Zhu, T Patel, JA Miller, CD Torrice… - International Journal of …, 2020 - mdpi.com
… differences in the severity of potential drug–drug interactions … Significant differences
between CYP3A4*1/*1 and patients … pharmacokinetics and incorporated pharmacogenetics …
between CYP3A4*1/*1 and patients … pharmacokinetics and incorporated pharmacogenetics …