A phase 1b study of the MET inhibitor capmatinib combined with cetuximab in patients with MET-positive colorectal cancer who had progressed following anti-EGFR …
… to anti-epidermal growth factor receptor (EGFR) monoclonal … In this phase 1b multicenter,
open-label, dose-finding study (… phase 2 dose of 400 mg that had previously been selected in …
open-label, dose-finding study (… phase 2 dose of 400 mg that had previously been selected in …
… blockade with cetuximab and erlotinib combined with anti-VEGF antibody bevacizumab in advanced solid tumors: a phase 1 dose escalation triplet combination trial
… A triplet combination of epidermal growth factor receptor (EGFR) monoclonal antibody and
… The dose-escalation portion of the study determined the recommended phase II dose (RP2D…
… The dose-escalation portion of the study determined the recommended phase II dose (RP2D…
[HTML][HTML] A randomized phase II study comparing the efficacy and safety of the glyco-optimized anti-EGFR antibody tomuzotuximab against cetuximab in patients with …
K Klinghammer, J Fayette, A Kawecki, A Dietz… - ESMO open, 2021 - Elsevier
… the addition of the epidermal growth factor receptor (EGFR) antibody cetuximab to a cisplatin
… The RESGEX study was a phase II, randomized, controlled, open-label, multicenter study of …
… The RESGEX study was a phase II, randomized, controlled, open-label, multicenter study of …
Phase II study of tivantinib and cetuximab in patients with KRAS wild-type metastatic colorectal cancer with acquired resistance to EGFR inhibitors and emergence of …
L Rimassa, S Bozzarelli, F Pietrantonio, S Cordio… - Clinical colorectal …, 2019 - Elsevier
… receptor tyrosine kinase, and cetuximab may be effective in patients with epidermal growth
factor receptor… This multicenter, single-arm, Simon 2-stage, phase II study enrolled patients …
factor receptor… This multicenter, single-arm, Simon 2-stage, phase II study enrolled patients …
[HTML][HTML] Implementing anti-epidermal growth factor receptor (EGFR) therapy in metastatic colorectal cancer: challenges and future perspectives
E Martinelli, D Ciardiello, G Martini, T Troiani… - Annals of …, 2020 - Elsevier
… Epidermal growth factor receptor (EGFR) inhibitors are … Anti-EGFR monoclonal antibodies
(MoAbs), such as cetuximab or … VELO is a multicenter randomized phase II trial which is …
(MoAbs), such as cetuximab or … VELO is a multicenter randomized phase II trial which is …
… phase 2 study of temsirolimus and cetuximab versus temsirolimus alone in recurrent/metastatic, cetuximab‐resistant head and neck cancer: The MAESTRO study
TY Seiwert, S Kochanny, K Wood, FP Worden… - Cancer, 2020 - Wiley Online Library
… This study hypothesized that dual blockade of mammalian target of rapamycin and epidermal
growth factor receptor (… In this multicenter, randomized clinical study, patients with recurrent/…
growth factor receptor (… In this multicenter, randomized clinical study, patients with recurrent/…
Phase II multi-institutional clinical trial result of concurrent cetuximab and nivolumab in recurrent and/or metastatic head and neck squamous cell carcinoma
… conducted a phase II multi-institutional clinical trial to determine … treated with a combination
of cetuximab and nivolumab. In … Open-label, uncontrolled, multicenter phase II study to …
of cetuximab and nivolumab. In … Open-label, uncontrolled, multicenter phase II study to …
Randomized Trial of Afatinib Plus Cetuximab Versus Afatinib Alone for First-Line Treatment of EGFR-Mutant Non–Small-Cell Lung Cancer: Final Results From SWOG …
SB Goldberg, MW Redman, R Lilenbaum… - Journal of Clinical …, 2020 - ascopubs.org
… were enrolled in this phase II, multicenter trial and randomly assigned to receive afatinib
40 mg orally daily plus cetuximab 500 mg/m 2 intravenously every 2 weeks or afatinib alone. …
40 mg orally daily plus cetuximab 500 mg/m 2 intravenously every 2 weeks or afatinib alone. …
[HTML][HTML] Anti-epidermal growth factor receptor (EGFR) monoclonal antibody combined with cisplatin and 5-fluorouracil in patients with metastatic nasopharyngeal …
C Zhao, J Miao, G Shen, J Li, M Shi, N Zhang, G Hu… - Annals of …, 2019 - Elsevier
… On this note, nimotuzumab, an anti-EGFR mAb like cetuximab… a multicentre, open-label phase
II clinical trial investigating … chemotherapy for rmNPC at the time of study design [15, 16]. In …
II clinical trial investigating … chemotherapy for rmNPC at the time of study design [15, 16]. In …
[HTML][HTML] Anti-epidermal growth factor receptor (EGFR) monoclonal antibody combined with chemoradiotherapy for induction chemotherapy resistant locally advanced …
X Niu, P Liu, X Zhou, D Ou, X Wang, C Hu - Translational Oncology, 2024 - Elsevier
… [15] demonstrated that adding cetuximab to CCRT did not improve outcome for stage III to IV
… So, we designed a single-arm, open-label phase II clinical trial investigating the efficacy and …
… So, we designed a single-arm, open-label phase II clinical trial investigating the efficacy and …