A phase II study alternating erlotinib with second-line mFOLFOX6 or FOLFIRI for metastatic colorectal cancer

MR Kearney, EY Chen, GM Vaccaro… - Anticancer …, 2019 - ar.iiarjournals.org
FOLFOX6 (mFOLFOX6) or FOLFIRI that they had not … of 18% (two out of 11 patients) in this
phase II trial testing erlotinib in … in patients with advanced solid tumors. Clin Cancer Res 13(…

A phase II and biomarker study of sorafenib combined with modified FOLFOX in patients with advanced hepatocellular carcinoma

L Goyal, H Zheng, TA Abrams, R Miksad… - Clinical Cancer …, 2019 - AACR
… In a phase II trial in patients with advanced hepatocellular carcinoma (HCC), the … treatment
for metastatic colon cancer in the RESPECT trial, a randomized phase II trial of mFOLFOX6 …

[HTML][HTML] … phase II study of planned discontinuation or continuous treatment of oxaliplatin after six cycles of modified FOLFOX6 plus panitumumab in patients with …

Y Munemoto, M Nakamura, M Takahashi… - European Journal of …, 2019 - Elsevier
… Chemotherapy-naive patients with RAS wild-type mCRC, aged ≥20 years, were enrolled
… of modified FOLFOX6 (mFOLFOX6) plus panitumumab as induction therapy. Patients who …

Efficacy of aflibercept with FOLFOX and maintenance with fluoropyrimidine as first‑line therapy for metastatic colorectal cancer: GERCOR VELVET phase II study

B Chibaudel, JB Bachet, T André… - International …, 2019 - spandidos-publications.com
… with previously untreated with unresectable advanced CRC ranges from 25 to 30 months,
when … Patients received intravenously modified FOLFOX7 with aflibercept as induction therapy …

Update on optimal treatment for metastatic colorectal cancer from the AGITG expert meeting: ESMO congress 2019

DK Lau, M Burge, A Roy, I Chau, DG Haller… - Expert review of …, 2020 - Taylor & Francis
… inhibitor (TKI) erlotinib to bevacizumab as maintenance … In a phase II trial, 153 patients
with KRAS exon 2 WT mCRC … , in a phase 1a/1b trial of patients with advanced CEA-positive…

A phase II study to explore biomarkers for the use of mFOLFOX6/XELOX plus bevacizumab as a first-line chemotherapy in patients with metastatic colorectal cancer …

W Okamoto, K Sakai, A Makiyama, Y Yamamoto… - ESMO open, 2022 - Elsevier
… clinical benefits of BV in patients with advanced gastric 11 and … in mCRC patients treated
with modified FOLFOX6 plus BV (… This study was a multicenter, single-arm, phase II trial

… reference bevacizumab in combination with XELOX or mFOLFOX6 as first-line treatment for metastatic colorectal cancer: results of a randomized, double-blind phase …

S Qin, J Li, Y Bai, Y Shu, W Li, X Yin, Y Cheng, G Sun… - BioDrugs, 2021 - Springer
… of reference bevacizumab in patients with mCRC. The primary objective of this trial was
to … (XELOX [capecitabine plus oxaliplatin] or modified FOLFOX6 [mFOLFOX6: 5-fluorouracil, …

Retrospective comparison of efficacy and safety of CAPOX and FOLFOX regimens as adjuvant treatment in patients with stage III colon cancer

S Degirmencioglu, O Tanrıverdi… - Journal of …, 2019 - journals.sagepub.com
… high-risk stage II, stage III, and stage IV cases for almost 2 decades. … The modified FOLFOX-6
regimen was used in this study. … in patients with locally advanced (stage III) colon cancer. …

[HTML][HTML] Relationship between progression-free survival and overall survival in randomized clinical trials of targeted and biologic agents in oncology

LM Hess, A Brnabic, O Mason, P Lee, S Barker - Journal of Cancer, 2019 - ncbi.nlm.nih.gov
… the two outcomes, while in others, like sarcoma, advanced breast cancer, prostate cancer
and NSCLC, the relationship is less clear 2 , 3 . … Phase II randomized study of vandetanib plus …

[HTML][HTML] Second-line treatment options for patients with metastatic pancreatic ductal adenocarcinoma: A systematic literature review

F Dayyani, T Macarulla, A Johnson… - Cancer Treatment …, 2023 - Elsevier
trial, the modified FOLFOX6 regimen did not provide additional efficacy compared with 5-
FU/LV in patients with advanced … ®) include combination erlotinib plus gemcitabine among its …