… A considerable number of studies have shown that inhibition of VEGF production can suppress
CNV … or whether it is a protective attempt to diminish excessive retinal neovascularization. …

… -neovascular (dry, nonexudative) AMD or the less prevalent … an increased pigment
epithelium-derived factor (PEDF) and … Bevacizumab binds and inhibits all isoforms of VEGF, but …

… VEGFand ischemia-induced endothelial progenitor cells (EPCs) … migration of EPCs towards
neovascularization sites through the … Pigment epithelium-derived factor inhibits advanced …

… during DR, such as pigment epithelium-derived factor (PEDF), … of VEGF and subsequently
retinal neovascularization (22, 23). … , it inhibits angiogenesis and neovascularization in the …

… , prevents ischemia-induced apoptosis and improves retinal … population in the retina while
the “wet” or “neovascular” form … ERK signaling suppression is apparently crucial for MG cell …

… resulting from occlusion of retinal veins and plays an … , as well as neovascularization of the
retina, optic disc, or the … but causes a pan-suppression of aqueous inflammatory mediators (…

… angiogenic factors to mediate retinal neovascularization (… retinal ECs and in retinas of
diabetic rats, while restoring miR-126 expression inhibits the hypoxia-induced neovascularization …

… to ameliorate ischemia-induced neovascularization were … -ß1-mediated suppression of
excessive neovascularization in an … epithelium-derived factor, brain-derived neurotrophic factor, …

… and pigment epithelium-derived factor (PEDF) as … Pigment epithelium-derived factor (PEDF)
is an effective angiogenic inhibitor that could inhibit the expression of VEGF and suppress …

… retinal neovascularization [66]. This evidence was also supported by the results obtained in
a mouse model of ischemia-induced retinal neovascularization… ) can suppress uveitis in mice…