… investigations to explore the efficacy of quercetin and folacin in experimental diabetes induced vascular endothelium dysfunction and associated dementia in rats

P Sharma, K Aggarwal, R Awasthi… - Journal of Basic and …, 2023 - degruyter.com
… less prone to endothelial dysfunction, cognitive impairment, and associated dementia-like …
levels, reduced body weight, learning memory, and impaired endothelial function in rats. STZ …

[HTML][HTML] Chemicals used for the induction of Alzheimer's disease-like cognitive dysfunctions in rodents

O Mahdi, MTH Baharuldin, NHM Nor… - Biomedical Research …, 2019 - biomedpress.org
… and subsequently lead to dementia. One of such age-related disorders is Alzheimer’s …
multifactorial forms of dementia characterized by multiple cognitive impairments, personality …

Beneficial effect of lupeol and metformin in mouse model of intracerebroventricular streptozotocin induced dementia

K Ram, K Kumar, D Singh, D Chopra, V Mani… - Metabolic Brain …, 2024 - Springer
Dementia is a clinical condition marked by the presence of enduring cognitive deficits,
encompassing impairments in memory, language, motor function, and object recognition, without …

… memory deficits, oxidative stress, endothelial dysfunction and neuropathological changes in rat model of hyperhomocysteinemia induced vascular dementia

P Bhatia, N Singh - International Journal of Neuroscience, 2022 - Taylor & Francis
… and Icariin have been reported to reverse cognitive impairment and improve learning and
memory deficits in various animal models of experimental dementia [Citation19]. In addition, …

Evaluation of involvement of adrenergic receptor modulator in hypertension induced experimental Vascular Dementia in Rats

BM Sharma, B Sharma - Research Journal of Pharmacy and …, 2021 - indianjournals.com
Pitavastatin and 4′-hydroxy-3methoxyacetophenone (HMAP) reduce cognitive dysfunction
in vascular dementia during experimental diabetes. Current Neurovascular Research. …

Neurobehavioral and neurobiochemical effect of atomoxetine and N-acetylcysteine in streptozotocin diabetes induced endothelial dysfunction and related dementia

H Aggarwal, S Gupta, P Sharma, BM Sharma… - Physiology & …, 2022 - Elsevier
Dementia is characterized by cognitive impairment, which is quantified as deficit in memory,
cognition, executive function, … Dementia of vascular origin occurs as a result of an impaired …

[HTML][HTML] Effect of Garcinia mangostana pericarp extract on glial NF‑κB levels and expression of serum inflammation markers in an obese‑type 2 diabetes mellitus …

M Muniroh, Y Nindita, V Karlowee… - Biomedical …, 2021 - spandidos-publications.com
… Type 2 diabetes mellitus (T2DM) has become a major public health issue and is
associated with a high incidence of cognitive impairment and dementia disorders, particularly …

Nasal Administration of bFGF-Loaded Nanoliposomes Attenuates Neuronal Injury and Cognitive Deficits in Mice with Vascular Dementia Induced by Repeated …

M Zhang, S Huang, W He, W Cao, M Sun… - International Journal of …, 2024 - Taylor & Francis
… Behavioral and histopathological analyses showed that cognitive function was significantly
improved in the bFGF-lips group compared to the VD and bFGF groups; in addition, …

[PDF][PDF] DEMENTIA: A NEURODEGENERATIVE DISORDER

A Srivastava, R Singh - researchgate.net
4hydroxy-3‟-methoxyacetophenone (HMAP), an NADPH oxidase … : Pitavastatin and
4‟-Hydroxy-3methoxyacetophenone (HMAP) reduce cognitive dysfunction in vascular dementia

[HTML][HTML] Hyperglycemia-driven neuroinflammation compromises BBB leading to memory loss in both diabetes mellitus (DM) type 1 and type 2 mouse models

S Rom, V Zuluaga-Ramirez, S Gajghate, A Seliga… - Molecular …, 2019 - Springer
… In order to evaluate cognitive function in DM models, we used two well-established tests,
Y maze and MWM. The Y maze spontaneous alternation paradigm is based on the ordinary …