The importance of lipoprotein lipase regulation in atherosclerosis

A Kumari, KK Kristensen, M Ploug, AML Winther - Biomedicines, 2021 - mdpi.com
Lipoprotein lipase (LPL) plays a major role in the lipid … and other factors involved in
intravascular lipolysis are also … of remnant lipoproteins from plasma and promote lipoprotein

Modified lipoproteins induce arterial wall inflammation during atherogenesis

MB Lorey, K Öörni, PT Kovanen - Frontiers in cardiovascular …, 2022 - frontiersin.org
… by lipoproteins isolated from atherosclerotic lesions having oxidized … -coated collagen via
lipoprotein lipase thereby leading to … are present in plasma (255) as well as in atherosclerotic

[HTML][HTML] The role of lipids and lipoproteins in atherosclerosis

MRF Linton, PG Yancey, SS Davies, WG Jerome… - Endotext …, 2019 - ncbi.nlm.nih.gov
… marrow accelerates atherosclerotic lesion development without affecting plasma cholesterol
… hydrolysis of triglycerides by lipoprotein lipase (LPL) and hepatic lipase (Figure 6). In …

[HTML][HTML] Impact of serum levels of lipoprotein lipase, hepatic lipase, and endothelial lipase on the progression of coronary artery disease

H Han, D Dai, W Wang, J Zhu, Z Zhu, L Lu… - Journal of Interventional …, 2019 - Elsevier
… Besides, these enzymes might exert a direct influence on an atherosclerotic plaque and its
… The physiological function of LPL is to catalyze the hydrolysis of triglycerides in plasma TRLs …

[PDF][PDF] The Importance of Lipoprotein Lipase Regulation in Atherosclerosis. Biomedicines 2021, 9, 782

A Kumari, KK Kristensen, M Ploug, AL Winther - 2021 - moodle2.units.it
… Abstract: Lipoprotein lipase (LPL) plays a major role in the lipid homeostasis mainly by …
Lipoprotein lipase in human plasma is mainly inactive and associated with cholesterol-rich …

[HTML][HTML] Biochemistry, lipoprotein lipase

Y Pirahanchi, MD Anoruo, S Sharma - StatPearls [Internet], 2023 - ncbi.nlm.nih.gov
… Clinically, LPL plays a significant role in the progression of atherosclerosis. LPL is a …
atherosclerosis were found to have elevated LPL mass and activity in their post-heparin plasma. …

Lipoprotein (a) in atherosclerotic diseases: from pathophysiology to diagnosis and treatment

S Lampsas, M Xenou, E Oikonomou, P Pantelidis… - Molecules, 2023 - mdpi.com
… Elevated lipoprotein(a) (Lp(a)) in plasma is an independent, … the role of Lp(a) in inflammation,
atherosclerosis and … and monoacylglycerols (via cleavage by lipoprotein lipase), can be …

[HTML][HTML] The functional role of lipoproteins in atherosclerosis: novel directions for diagnosis and targeting therapy

Y Lu, X Cui, L Zhang, X Wang, Y Xu, Z Qin… - Aging and …, 2022 - ncbi.nlm.nih.gov
… Most of the triglycerides are removed by lipoprotein lipase leading to the VLDLs’ transformation
Several studies have identified that raised plasma LDL levels results in the initiation and …

Triglyceride-rich lipoproteins: their role in atherosclerosis

Y Castillo-Núñez, E Morales-Villegas… - Revista de …, 2022 - scielo.org.mx
… Furthermore, plasma accumulation of TRLs causes hyperviscosity and a procoagulant state.
… (mainly, lipoprotein lipase [LPL]). The chylomicron end products are known as remnants; …

Role of LpL (lipoprotein lipase) in macrophage polarization in vitro and in vivo

HR Chang, T Josefs, D Scerbo, N Gumaste… - Arteriosclerosis …, 2019 - Am Heart Assoc
… Inducible lipoprotein lipase (iLpl) deletion increased plasma triglyceride (TG) level, circulating
Ly6C hi monocytes level, and anti-inflammatory genes in monocyte despite more lipid …