PASylated thymosin α1: a long-acting immunostimulatory peptide for applications in oncology and virology

U Binder, A Skerra - International Journal of Molecular Sciences, 2020 - mdpi.com
… to produce a long-acting version of Tα1 in Escherichia coli at … by optimizing the expression
plasmid and the production process, … covering a wide range of physiological functions [61], …

[HTML][HTML] Characterizing conjugative plasmids from an antibiotic-resistant dataset for use as broad-host delivery vectors

HG Loyola Irizarry, IL Brito - Frontiers in Microbiology, 2023 - frontiersin.org
… -associated genes, plasmid stability and maintenance genes, and … 98 plasmids encoding
Psi genes and 89 plasmids encoding MPS genes. The most common Psi gene was psiB, while

TMAVA, a metabolite of intestinal microbes, is increased in plasma from patients with liver steatosis, inhibits γ-butyrobetaine hydroxylase, and exacerbates fatty liver in …

M Zhao, L Zhao, X Xiong, Y He, W Huang, Z Liu, L Ji… - Gastroenterology, 2020 - Elsevier
… —and through increased inflammation, hepatocyte injury, and … or smolder at a relatively
constant pace towards cirrhosis. It … plays an important role in physiological homeostasis. The rate…

[PDF][PDF] Hepatic cytochrome P450 8B1 and cholic acid potentiate intestinal epithelial injury in colitis by suppressing intestinal stem cell renewal

L Chen, T Jiao, W Liu, Y Luo, J Wang, X Guo, X Tong… - Cell Stem Cell, 2022 - cell.com
… -OE colitic mice produced fewer outgrowths when cultured ex vivo… on the physiological
function of intestinal epithelium. … 3 after DSS, while hepatic CYP8B1 expression continued to rise, …

Discovery and structure of a widespread bacterial ABC transporter specific for ergothioneine

Y Zhang, G Gonzalez-Gutierrez, KA Legg… - Nature …, 2022 - nature.com
… In the meantime, to ensure continued support, we are … rather than the thiol tautomer at
physiological pH 7 (Supplementary Fig. … F1 containing SpEgtUC and pSUMO plasmid (6.5 kB) was …

Biological effects of indole-3-propionic acid, a gut microbiota-derived metabolite, and its precursor tryptophan in mammals' health and disease

P Konopelski, I Mogilnicka - International journal of molecular sciences, 2022 - mdpi.com
… a comprehensive review of the physiological roles of IPA, and … after phosphatidylcholine-
and L-carnitine-rich meals [53], and … Serotonin produced in the gut is released into the blood …

Regulation of biological processes by intrinsically chiral engineered materials

B Ma, A Bianco - Nature Reviews Materials, 2023 - nature.com
… -CDs in transforming supercoiled plasmid DNA into a nicked open-… In normal physiological
conditions, Topo I relaxes … enantiomers (l-DOPA, l-carnitine, d-carnitine and doxorubicin) on …

Adaptive Response of Listeria monocytogenes to the Stress Factors in the Food Processing Environment

…, K Grudlewska-Buda, E Wałecka-Zacharska… - Frontiers in …, 2021 - frontiersin.org
… The stress conditions encountered during food production and … Depending on the physiological
state of the cell, inactivation of … Plasmids were more frequently isolated from food strains

Exploring Probiotic Potential: A Comparative Genomics and In Silico Assessment of Genes within the Genus Geobacillus

IN Najar, P Sharma, R Das, K Mondal, AK Singh… - bioRxiv, 2024 - biorxiv.org
… genus exhibits ecological, physiological, and genetic diversity, 389 merely … However, in our
study, we did not find any plasmid in the … The mazEF module, found 569 on Escherichia coli's

[PDF][PDF] Promoter characterization for metabolic engineering in Methanococcus maripaludis

E de Dios Mateos - 2023 - helda.helsinki.fi
… to produce isoprenoids has been altered through metabolic … All plasmids and strains used
in this study are listed in Tables … and promoting DNA repair via homologous recombination …