The immunosuppressive effect of the endocannabinoid system on the inflammatory phenotypes of macrophages and mesenchymal stromal cells: a comparative study
T Ruhl, C Corsten, JP Beier, BS Kim - Pharmacological Reports, 2021 - Springer
… Succesful polarization was detected by secreted soluble … and exhibited a typical
spindle-shaped morphology (Fig. 1a). … , but no cannabinoid compound affected the production of …
spindle-shaped morphology (Fig. 1a). … , but no cannabinoid compound affected the production of …
[HTML][HTML] Characterisation and localisation of the endocannabinoid system components in the adult human testis
JE Nielsen, AD Rolland, E Rajpert-De Meyts… - Scientific reports, 2019 - nature.com
… The cannabinoid receptors, CNR1 and CNR2 were detected at … the protein expression
pattern of the endocannabinoid-… of the MGLL staining was somewhat polarised, weakest near …
pattern of the endocannabinoid-… of the MGLL staining was somewhat polarised, weakest near …
[HTML][HTML] The C-terminal helix 9 motif in rat cannabinoid receptor type 1 regulates axonal trafficking and surface expression
A Fletcher-Jones, KL Hildick, AJ Evans, Y Nakamura… - Elife, 2019 - elifesciences.org
… to make the receptors available to bind endocannabinoids. … somatodendritic compartment
and is not detected in the proximal 50 µm of … axonally polarised, the degree of polarisation was …
and is not detected in the proximal 50 µm of … axonally polarised, the degree of polarisation was …
[HTML][HTML] Protein interactors and trafficking pathways that regulate the cannabinoid type 1 receptor (CB1R)
A Fletcher-Jones, KL Hildick, AJ Evans… - Frontiers in molecular …, 2020 - frontiersin.org
… Endocannabinoid system signaling downstream of CB1R is … This review focuses on the
trafficking and polarized surface … the ER, intracellular CB1R is detected in the axon as soon as 25 …
trafficking and polarized surface … the ER, intracellular CB1R is detected in the axon as soon as 25 …
Cannabinoid and planar cell polarity signaling converges to direct placentation
YS Kim, Y Li, J Yuan, JP Borg… - Proceedings of the …, 2021 - National Acad Sciences
… endocannabinoids via G protein–coupled cannabinoid … The PCP pathway is best known
for its role in cell polarization at the … to CRE expression patterns, CRE activity was detected in …
for its role in cell polarization at the … to CRE expression patterns, CRE activity was detected in …
[HTML][HTML] The endocannabinoid system in the visual process
SJ Pasquaré, E Chamorro-Aguirre… - Journal of Photochemistry …, 2023 - Elsevier
… (cAMP) production is a characteristic response of cannabinoid … In mice retina, DAGLα was
detected in OFF bipolar cells type 1 … This figure shows how cannabinoid-related enzymes and …
detected in OFF bipolar cells type 1 … This figure shows how cannabinoid-related enzymes and …
[HTML][HTML] Cannabinoids regulate sensory processing in early olfactory and visual neural circuits
T Heinbockel, A Straiker - Frontiers in neural circuits, 2021 - frontiersin.org
… , the endogenous cannabinoids or endocannabinoids, also … The authors found a THC effect
on both olfactory detection thresholds and … polarization, subsequent changes in calcium and …
on both olfactory detection thresholds and … polarization, subsequent changes in calcium and …
Endocannabinoid signaling in brain diseases: Emerging relevance of glial cells
A Bernal‐Chico, V Tepavcevic, A Manterola, C Utrilla… - Glia, 2023 - Wiley Online Library
… and cellular hallmarks of endocannabinoid signaling in glial … MAGL and FAAH have also
been detected at the intracellular … of cannabinoid receptors and classical endocannabinoids …
been detected at the intracellular … of cannabinoid receptors and classical endocannabinoids …
Imaging the endocannabinoid signaling system
… receptor of endocannabinoids, the cannabinoid type-1 … mechanisms that may shape their
nanoscale distribution … , GRAB sensors revolutionized the detection of bioactive compounds in …
nanoscale distribution … , GRAB sensors revolutionized the detection of bioactive compounds in …
[HTML][HTML] On the influence of cannabinoids on cell morphology and motility of glioblastoma cells
T Hohmann, K Feese, C Ghadban, F Dehghani… - PLoS …, 2019 - journals.plos.org
… treatments had no effect on the movement pattern of LN229 … , resulting in a more circular
cell shape. For U87 cells only the … Thereby, no significant changes were detected. An example …
cell shape. For U87 cells only the … Thereby, no significant changes were detected. An example …