… Our aim was to test associations between genetic polymorphisms involved in the absorption
and metabolism of CsA and TAC, and drug disposition variables in two groups of Chilean …

… data obtained from Spanish Caucasians, particularly from the northern region of Spain and
to the … Influence of genotype and haplotype of MDR1 (C3435T, G2677A/T, C1236T) on the …

… The present meta-analysis is performed to determine the association of C1236T and
C3435T polymorphisms in the MDR1 gene. Google Scholar, PubMed, and Science Direct were …

… The human MDR1 gene mutation at exon 26, position 3435 (also known as C3435T) leads
… Although the C3435T mutation in exon 26 of the MDR1 gene is a silent mutation, this poly‑ …

… Thus, the objective of this candidate-gene study was to investigate the effect of 72
polymorphisms in 21 genes on olanzapine pharmacokinetics and safety, including transporters (eg …

… three ABCB1 common polymorphisms (ie, C3435T, or rs1045642… The protocol complied with
current Spanish legislation on … human MDR1 drug efflux transporter and genetic variation of …

… most commonly studied reduced-function single nucleotide polymorphism (SNP) is *20, …
highly polymorphic enzyme as CYP3A4*20 allele was present in 1.2% of the Spanish population …

… ABCB1 common polymorphisms (ie, C3435T, or … Spanish legislation on clinical research
in humans and was approved by the Research Ethics Committee, authorized by the Spanish …

… The three genetic variants C1236T, G2677T/A, and C3435T … the C1236T and C3435T
variants generate conformational … , G2677T/A, and C3435T variants plays a crucial role in P-gp …

… In Spain, the five-year relative survival has been estimated to be around 20% [2]. This … of
AML and the influence of patients’ genetic polymorphisms is needed to help shed light on the …