Beyond Single Nucleotide Polymorphisms: CYP3A5367 Composite and ABCB1 Haplotype Associations to Tacrolimus Pharmacokinetics in Black and White …

DA Brazeau, K Attwood, CJ Meaney, GE Wilding… - … in Genetics, 2020 - frontiersin.org
… nucleotide polymorphisms: 1236C > T (rs1128503), 2677G > T/A(rs2032582), and 3435C
> T(rs1045642). Finally, a combined analysis using both CYP3A5 and ABCB1 polymorphisms

[PDF][PDF] Research Article Frequency of CYP2B6 Alleles in Major Iranian Ethnicities, Affecting Response to Efavirenz

P Mardi, B Tavakoli-Far, SS Nia, R Jazayeri… - 2022 - academia.edu
… humans is encoded by the CYP2B6 gene. Polymorphisms of this gene play a crucial role in
… frequencies of the CYP2B6 gene between Spaniards and Central Americans. ey showed …

Predictive value of ERCC2, ABCC2 and MMP2 of response and long-term survival in locally advanced head and neck cancer patients treated with …

G Duran, R Cruz, S Aguín, F Barros… - Cancer Chemotherapy …, 2021 - Springer
… in several diseases and the most studied is the C3435T located in exon 26, that encodes for
P-… , our results show associations between polymorphisms in DNA repair genes and genetic

Genetic factors influencing the development of vincristine-induced neurotoxicity

E Pozzi, G Fumagalli, A Chiorazzi, A Canta… - Expert Opinion on …, 2021 - Taylor & Francis
… In this study based on large Spanish children cohort (n = 179) with B-ALL one interesting
polymorphism was found: rs12402181 in the seed region of miR-3117-3p. This SNP, …

Effects of comedication and genetic factors on the population pharmacokinetics of lamotrigine: a prospective analysis in Chinese patients with epilepsy

Z Wang, Y Zhang, W Huang, X Wang, X Ni… - Frontiers in …, 2019 - frontiersin.org
… patients with different gene polymorphisms and comedications … data, MDR1-2677TT carriers
were likely to have C3435T TT … The MDR1 gene encodes a 170-kDa cellular efflux pump for …

The impact of genetic factors on the response to migraine therapy

D Tsirelis, A Tsekouras, P Stamati… - Reviews in the …, 2024 - degruyter.com
gene polymorphisms CYP2D6 or CYP2C19. Similarly, for the treatment response to VA, no
significant correlation was found with the gene polymorphisms MDR1C3435T polymorphism

The role of pharmacogenetics in antithrombotic therapy management: new achievements and barriers yet to overcome

V Conti, G Corbi, V Manzo, C Sellitto… - Current Medicinal …, 2021 - ingentaconnect.com
polymorphisms in MDR1, UGT1A1, and APOE genes [36, 37]. Some polymorphisms in the
APOE gene … Several studies have shown that the polymorphism ABCB1 C3435T influences …

[PDF][PDF] Clopidogrel Pharmacogenetics in Patients Undergoing Percutaneous Neurointervention

M Saiz-Rodríguez, F Abad-Santos - J Neurobiol Physiol, 2020 - probiologists.com
… The most commonly studied variant in ABCB1 is C3435T. Several studies have evaluated
the influence of C3435T polymorphism on clopidogrel treatment. Taubert et al. described …

Are gene polymorphisms related to adverse events of methotrexate in patients with rheumatoid arthritis? A retrospective cohort study based on an updated meta …

J Huang, H Fan, Q Qiu, K Liu, S Lv, J Li… - … in Chronic Disease, 2020 - journals.sagepub.com
Aims: We performed an updated meta-analysis to verify correlations between gene polymorphisms
and adverse events in methotrexate (MTX)-treated rheumatoid arthritis (RA) patients. …

Pharmacogenetics: a comprehensive review of genes, genetics, genomics, and epigenetics

Y Kawji, H Almoaswes, CA Bise, L Kawji… - Substance Use and …, 2023 - Elsevier
… three polymorphisms are in linkage disequilibrium in the Caucasian population [36]. Interestingly,
the C3435T polymorphism … For instance, overexpression of the MDR1 gene product, P-…