Beyond Single Nucleotide Polymorphisms: CYP3A5∗3∗6∗7 Composite and ABCB1 Haplotype Associations to Tacrolimus Pharmacokinetics in Black and White …
DA Brazeau, K Attwood, CJ Meaney, GE Wilding… - … in Genetics, 2020 - frontiersin.org
… nucleotide polymorphisms: 1236C > T (rs1128503), 2677G > T/A(rs2032582), and 3435C
> T(rs1045642). Finally, a combined analysis using both CYP3A5 and ABCB1 polymorphisms …
> T(rs1045642). Finally, a combined analysis using both CYP3A5 and ABCB1 polymorphisms …
[PDF][PDF] Research Article Frequency of CYP2B6 Alleles in Major Iranian Ethnicities, Affecting Response to Efavirenz
… humans is encoded by the CYP2B6 gene. Polymorphisms of this gene play a crucial role in
… frequencies of the CYP2B6 gene between Spaniards and Central Americans. ey showed …
… frequencies of the CYP2B6 gene between Spaniards and Central Americans. ey showed …
Predictive value of ERCC2, ABCC2 and MMP2 of response and long-term survival in locally advanced head and neck cancer patients treated with …
G Duran, R Cruz, S Aguín, F Barros… - Cancer Chemotherapy …, 2021 - Springer
… in several diseases and the most studied is the C3435T located in exon 26, that encodes for
P-… , our results show associations between polymorphisms in DNA repair genes and genetic …
P-… , our results show associations between polymorphisms in DNA repair genes and genetic …
Genetic factors influencing the development of vincristine-induced neurotoxicity
E Pozzi, G Fumagalli, A Chiorazzi, A Canta… - Expert Opinion on …, 2021 - Taylor & Francis
… In this study based on large Spanish children cohort (n = 179) with B-ALL one interesting
polymorphism was found: rs12402181 in the seed region of miR-3117-3p. This SNP, …
polymorphism was found: rs12402181 in the seed region of miR-3117-3p. This SNP, …
Effects of comedication and genetic factors on the population pharmacokinetics of lamotrigine: a prospective analysis in Chinese patients with epilepsy
Z Wang, Y Zhang, W Huang, X Wang, X Ni… - Frontiers in …, 2019 - frontiersin.org
… patients with different gene polymorphisms and comedications … data, MDR1-2677TT carriers
were likely to have C3435T TT … The MDR1 gene encodes a 170-kDa cellular efflux pump for …
were likely to have C3435T TT … The MDR1 gene encodes a 170-kDa cellular efflux pump for …
The impact of genetic factors on the response to migraine therapy
D Tsirelis, A Tsekouras, P Stamati… - Reviews in the …, 2024 - degruyter.com
… gene polymorphisms CYP2D6 or CYP2C19. Similarly, for the treatment response to VA, no
significant correlation was found with the gene polymorphisms MDR1… C3435T polymorphism …
significant correlation was found with the gene polymorphisms MDR1… C3435T polymorphism …
The role of pharmacogenetics in antithrombotic therapy management: new achievements and barriers yet to overcome
… polymorphisms in MDR1, UGT1A1, and APOE genes [36, 37]. Some polymorphisms in the
APOE gene … Several studies have shown that the polymorphism ABCB1 C3435T influences …
APOE gene … Several studies have shown that the polymorphism ABCB1 C3435T influences …
[PDF][PDF] Clopidogrel Pharmacogenetics in Patients Undergoing Percutaneous Neurointervention
M Saiz-Rodríguez, F Abad-Santos - J Neurobiol Physiol, 2020 - probiologists.com
… The most commonly studied variant in ABCB1 is C3435T. Several studies have evaluated
the influence of C3435T polymorphism on clopidogrel treatment. Taubert et al. described …
the influence of C3435T polymorphism on clopidogrel treatment. Taubert et al. described …
Are gene polymorphisms related to adverse events of methotrexate in patients with rheumatoid arthritis? A retrospective cohort study based on an updated meta …
J Huang, H Fan, Q Qiu, K Liu, S Lv, J Li… - … in Chronic Disease, 2020 - journals.sagepub.com
Aims: We performed an updated meta-analysis to verify correlations between gene polymorphisms
and adverse events in methotrexate (MTX)-treated rheumatoid arthritis (RA) patients. …
and adverse events in methotrexate (MTX)-treated rheumatoid arthritis (RA) patients. …
Pharmacogenetics: a comprehensive review of genes, genetics, genomics, and epigenetics
Y Kawji, H Almoaswes, CA Bise, L Kawji… - Substance Use and …, 2023 - Elsevier
… three polymorphisms are in linkage disequilibrium in the Caucasian population [36]. Interestingly,
the C3435T polymorphism … For instance, overexpression of the MDR1 gene product, P-…
the C3435T polymorphism … For instance, overexpression of the MDR1 gene product, P-…