[HTML][HTML] The potential role of genomic medicine in the therapeutic management of rheumatoid arthritis

M Acosta-Herrera, D González-Serna… - Journal of Clinical …, 2019 - mdpi.com
… were replicated in a Spanish independent sample, reaching … polymorphisms within the
nonclassical HLA-E gene … of the C3435T SNP of the multidrug-resistance 1 (MDR1) gene [53,54]. …

[HTML][HTML] Donor–Recipient Non-HLA Variants, Mismatches and Renal Allograft Outcomes: Evolving Paradigms

P Jethwani, A Rao, L Bow, MC Menon - Frontiers in Immunology, 2022 - frontiersin.org
… Donor ABCB1 polymorphisms have been associated with long-term kidney function among
… ABCB1 polymorphisms and allograft outcomes in kidney transplants from American, Spanish

Genetics and antiepileptic mood stabilizer treatment response in bipolar disorder: What do we know?

AMC Ho, RM Weinshilboum, MA Frye… - …, 2021 - Taylor & Francis
… Recently, we published the first GWAS of AED-MS treatment response in BD and discovered
several novel candidate genetic markers through single nucleotide polymorphism (SNP) …

[图书][B] Pharmacoresistance in epilepsy: from genes and molecules to promising therapies

LL Rocha, A Lazarowski, EA Cavalheiro - 2023 - books.google.com
… Information confirms that genetic differences may impact the pharmacokinetics of antiseizure
medications. Also, several haplotypes in the polymorphisms of enzymes and transporters …

Pharmacogenetic perspectives in improving pharmacokinetic profiles for efficient bioequivalence trials with highly variable drugs: A review

PJ Huang, Y Hsieh, YW Huang, L Ding… - International journal …, 2021 - Taylor & Francis
… Multiallelic genetic polymorphisms could be generally … on the applications of genetic
polymorphisms screen of the CYP … ) formulations (n = 70 healthy Spaniards with both genders) …

A Population Pharmacokinetic Model to Predict the Individual Starting Dose of Tacrolimus for Tunisian Adults after Renal Transplantation

A Abderahmene, MI Francke, LM Andrews… - Therapeutic Drug …, 2022 - journals.lww.com
… The model was validated internally in a Dutch population and externally in a Spanish
Polymorphic expression and ethnicity-specific activity of CYP3A5 alleles have been suggested to …

[HTML][HTML] Leveraging genetic findings for precision medicine in vasculitis

M Acosta-Herrera, MA González-Gay, J Martín… - Frontiers in …, 2019 - frontiersin.org
… ; whereas polymorphisms within the DPB1 and DPA1 genes … study performed in BD patients
from Spain (18). IL10 encodes a … an association between two SNPs, C3435T and G2677T/A, …

ABC family transporters

X Liu - Drug transporters in drug disposition, effects and …, 2019 - Springer
… Human P-GP is coded by MDR1 gene (ABCB1). Rodents have … gene encoding P-GP is
highly polymorphic. Till date, 66 coding single-nucleotide polymorphisms (SNPs) in ABCB1 gene

[HTML][HTML] General recommendation for assessment and management on the risk of glucocorticoid-induced osteonecrosis in patients with COVID-19

W Li, Z Huang, B Tan, G Chen, X Li, K Xiong… - Journal of orthopaedic …, 2021 - Elsevier
… The main findings of the current study were summarized as following: our meta-analysis
showed that 32% of patients with SARS had developed osteonecrosis after receiving …

Proton pump inhibitors in Iranian population: from clinical regimens to pharmacogenomics

K Bagherzadeh, S Safari, M Amanlou… - Physiology and …, 2020 - ppj.phypha.ir
… pattern of gene polymorphism that extremely … polymorphism that affect drug metabolism
involve oxidation by cytochrome P450 enzymes (CYP). CYP2C subfamily are encoded by genes