[HTML][HTML] The potential role of genomic medicine in the therapeutic management of rheumatoid arthritis
M Acosta-Herrera, D González-Serna… - Journal of Clinical …, 2019 - mdpi.com
… were replicated in a Spanish independent sample, reaching … polymorphisms within the
nonclassical HLA-E gene … of the C3435T SNP of the multidrug-resistance 1 (MDR1) gene [53,54]. …
nonclassical HLA-E gene … of the C3435T SNP of the multidrug-resistance 1 (MDR1) gene [53,54]. …
[HTML][HTML] Donor–Recipient Non-HLA Variants, Mismatches and Renal Allograft Outcomes: Evolving Paradigms
P Jethwani, A Rao, L Bow, MC Menon - Frontiers in Immunology, 2022 - frontiersin.org
… Donor ABCB1 polymorphisms have been associated with long-term kidney function among
… ABCB1 polymorphisms and allograft outcomes in kidney transplants from American, Spanish…
… ABCB1 polymorphisms and allograft outcomes in kidney transplants from American, Spanish…
Genetics and antiepileptic mood stabilizer treatment response in bipolar disorder: What do we know?
AMC Ho, RM Weinshilboum, MA Frye… - …, 2021 - Taylor & Francis
… Recently, we published the first GWAS of AED-MS treatment response in BD and discovered
several novel candidate genetic markers through single nucleotide polymorphism (SNP) …
several novel candidate genetic markers through single nucleotide polymorphism (SNP) …
[图书][B] Pharmacoresistance in epilepsy: from genes and molecules to promising therapies
… Information confirms that genetic differences may impact the pharmacokinetics of antiseizure
medications. Also, several haplotypes in the polymorphisms of enzymes and transporters …
medications. Also, several haplotypes in the polymorphisms of enzymes and transporters …
Pharmacogenetic perspectives in improving pharmacokinetic profiles for efficient bioequivalence trials with highly variable drugs: A review
PJ Huang, Y Hsieh, YW Huang, L Ding… - International journal …, 2021 - Taylor & Francis
… Multiallelic genetic polymorphisms could be generally … on the applications of genetic
polymorphisms screen of the CYP … ) formulations (n = 70 healthy Spaniards with both genders) …
polymorphisms screen of the CYP … ) formulations (n = 70 healthy Spaniards with both genders) …
A Population Pharmacokinetic Model to Predict the Individual Starting Dose of Tacrolimus for Tunisian Adults after Renal Transplantation
A Abderahmene, MI Francke, LM Andrews… - Therapeutic Drug …, 2022 - journals.lww.com
… The model was validated internally in a Dutch population and externally in a Spanish …
Polymorphic expression and ethnicity-specific activity of CYP3A5 alleles have been suggested to …
Polymorphic expression and ethnicity-specific activity of CYP3A5 alleles have been suggested to …
[HTML][HTML] Leveraging genetic findings for precision medicine in vasculitis
M Acosta-Herrera, MA González-Gay, J Martín… - Frontiers in …, 2019 - frontiersin.org
… ; whereas polymorphisms within the DPB1 and DPA1 genes … study performed in BD patients
from Spain (18). IL10 encodes a … an association between two SNPs, C3435T and G2677T/A, …
from Spain (18). IL10 encodes a … an association between two SNPs, C3435T and G2677T/A, …
ABC family transporters
X Liu - Drug transporters in drug disposition, effects and …, 2019 - Springer
… Human P-GP is coded by MDR1 gene (ABCB1). Rodents have … gene encoding P-GP is
highly polymorphic. Till date, 66 coding single-nucleotide polymorphisms (SNPs) in ABCB1 gene …
highly polymorphic. Till date, 66 coding single-nucleotide polymorphisms (SNPs) in ABCB1 gene …
[HTML][HTML] General recommendation for assessment and management on the risk of glucocorticoid-induced osteonecrosis in patients with COVID-19
W Li, Z Huang, B Tan, G Chen, X Li, K Xiong… - Journal of orthopaedic …, 2021 - Elsevier
… The main findings of the current study were summarized as following: our meta-analysis
showed that 32% of patients with SARS had developed osteonecrosis after receiving …
showed that 32% of patients with SARS had developed osteonecrosis after receiving …
Proton pump inhibitors in Iranian population: from clinical regimens to pharmacogenomics
… pattern of gene polymorphism that extremely … polymorphism that affect drug metabolism
involve oxidation by cytochrome P450 enzymes (CYP). CYP2C subfamily are encoded by genes …
involve oxidation by cytochrome P450 enzymes (CYP). CYP2C subfamily are encoded by genes …