Population pharmacokinetics of continuous infusion of piperacillin/tazobactam in very elderly hospitalized patients and considerations for target attainment against …

PG Cojutti, E Morandin, M Baraldo, F Pea - International journal of …, 2021 - Elsevier
… A growing level of evidence has emerged showing that the use of extended infusion or
continuous infusion (CI) PIP/TAZ may be more beneficial than standard intermittent 30-min …

Population pharmacokinetics and safety of piperacillin-tazobactam extended infusions in infants and children

C Thibault, J Lavigne, C Litalien, N Kassir… - Antimicrobial agents …, 2019 - Am Soc Microbiol
… AEs resolved without clinical consequence, and 19 (28%) were ongoing at discharge from
hospital or 30 days following the last extended-infusion dose if the child was still hospitalized. …

Population pharmacokinetics of piperacillin/tazobactam across the adult lifespan

M Hemmersbach-Miller, SJ Balevic, PL Winokur… - … pharmacokinetics, 2023 - Springer
… measured by the pre-hospitalization CSHA Clinical Frailty Scale recorded at enrollment) on
the pharmacokinetics of piperacillin/tazobactam [8]. Hospitalized adult patients who had an …

Piperacillin-tazobactam in intensive care units: a review of population pharmacokinetic analyses

I El-Haffaf, JA Caissy, A Marsot - Clinical pharmacokinetics, 2021 - Springer
… the population pharmacokinetic models developed for piperacillin-tazobactam and provides
… Simulations showed that continuous or extended infusion methods performed better than …

Population pharmacokinetics and dosing optimization of piperacillin-tazobactam in critically ill patients on extracorporeal membrane oxygenation and the influence of …

J Hahn, KL Min, S Kang, S Yang, MS Park… - Microbiology …, 2021 - Am Soc Microbiol
… based on a total daily piperacillin-tazobactam dose of 24/3, … bolus), 3 h or 4 h (extended
infusion duration equal to half of the … CCU at Severance Cardiovascular Hospital for their routine …

A population pharmacokinetics and pharmacodynamic approach to optimize tazobactam activity in critically ill patients

SN Kalaria, M Gopalakrishnan… - Antimicrobial agents and …, 2020 - Am Soc Microbiol
Hospitalized critically ill adult patients receiving piperacillin-tazobactam (TZP) for a culture-…
Target attainments of greater than 75% were achieved when using extended infusion times of …

Population pharmacokinetics of piperacillin following continuous infusion in critically ill patients and impact of renal function on target attainment

V Klastrup, A Thorsted, M Storgaard… - Antimicrobial agents …, 2020 - Am Soc Microbiol
… Furthermore, extended infusion seems to be beneficial in certain ICU … At the time when
piperacillin-tazobactam continuous infusion was initiated at the ICU at Aarhus University Hospital, …

Using a validated population pharmacokinetic model for dosing recommendations of continuous infusion piperacillin for critically ill adult patients

I El-Haffaf, R Guilhaumou, L Velly, A Marsot - Clinical Pharmacokinetics, 2022 - Springer
… by continuous (CI) or extended infusion over the more traditional intermittent bolus method.
Hospital, France. Patients admitted to this ICU and receiving piperacillin-tazobactam by CI …

Population pharmacokinetics of piperacillin/tazobactam in critically ill Korean patients and the effects of extracorporeal membrane oxygenation

YK Kim, HS Kim, S Park, H Kim… - Journal of …, 2022 - academic.oup.com
… tertiary referral hospital from September 2020 to April 2021 (Hallym University Sacred
Heart Hospital, Anyang, South Korea). Clinical indications for piperacillin/tazobactam included …

[PDF][PDF] Chapitre 2. Piperacillin-Tazobactam in Intensive Care Units: A Review of Population Pharmacokinetic Analyses

I El-Haffaf, JA Caissy, A Marsot - … de population, 2022 - papyrus.bib.umontreal.ca
… Administration and sampling methods for piperacillin-tazobactam in the studies included in
this review… Characteristics of the population pharmacokinetics models included in this review. …