Peptide-based inhibitors of fimbrial biogenesis in Porphyromonas gingivalis

SR Alaei, JH Park, SG Walker… - Infection and …, 2019 - Am Soc Microbiol
… assembly through a donor strand exchange mechanism, in which cleavage of the N-terminal
proregion opens an interactive surface for binding of a C-terminal donor strand from a …

[HTML][HTML] Porphyromonas gingivalis FimA and Mfa1 fimbriae: Current insights on localization, function, biogenesis, and genotype

Y Hasegawa, K Nagano - Japanese Dental Science Review, 2021 - Elsevier
… In general, the periodontal pathogen Porphyromonas gingivalis expresses distinct … fimbriae
may be responsible for the adhesive properties of P. gingivalis and enable it to bind host cells

[HTML][HTML] Oral mucosal epithelial cells

S Groeger, J Meyle - Frontiers in immunology, 2019 - frontiersin.org
… pathogenic bacteria such as Porphyromonas gingivalis (P. … specialized epithelial cells within
the gingiva show a distinct keratingingivalis fimbriae bind to cellular α5β1-integrin, which …

Role of Porphyromonas gingivalis in oral squamous cell carcinoma development: A systematic review

I Lafuente Ibáñez de Mendoza… - Journal of …, 2020 - Wiley Online Library
epithelial cells (Population) infected with P gingivalis (Intervention), compared to non-infected
OSCC or healthy oral epithelial cells (… of P gingivalis varied depending on fimA fimbriae. …

Porphyromonas gingivalis enhances pneumococcal adhesion to human alveolar epithelial cells by increasing expression of host platelet‐activating factor receptor

N Kamio, M Hayata, M Tamura, H Tanaka, K Imai - FEBS letters, 2021 - Wiley Online Library
… Bacterial binding to the epithelium subsequently causes … In addition, keratin 10, polymeric
immunoglobulin receptor and … We investigated three major components of CSP: LPS, fimbriae

[HTML][HTML] Pathogenesis of Important Virulence Factors of Porphyromonas gingivalis via Toll-Like Receptors

L Jia, N Han, J Du, L Guo, Z Luo, Y Liu - Frontiers in cellular and …, 2019 - frontiersin.org
… pathway on cell activity depends on mainly the binding of … Porphyromonas gingivalis long
fimbrial proteins were capable … gingivalis by epithelial cells, mCD14 can cause a more violent …

How Porphyromonas gingivalis Navigate the Map: The Effect of Surface Topography on the Adhesion of Porphyromonas gingivalis on Biomaterials

R Ardhani, R Diana, B Pidhatika - Materials, 2022 - mdpi.com
… an understanding of how Porphyromonas gingivalis responds to … could not adhere to both
epithelial cells or the gingival … These fimbriae help bind specifically to and trigger various …

Gingival epithelial barrier: regulation by beneficial and harmful microbes

N Takahashi, B Sulijaya, M Yamada-Hara… - Tissue …, 2019 - Taylor & Francis
… Amano et al. reported that P. gingivalis fimbriae mediate adherence to oral epithelial cells, …
gordonii has the Hsa sialic acid-binding protein that facilitates its binding to oral surfaces, thus …

Influence of periodontal pathogens on induction of epithelial-mesenchymal transition (EMT) in oral keratinocytes

SS Shoker - 2022 - etheses.bham.ac.uk
epithelial cells gain migratory and invasive properties and is associated with dissolution of
epithelial … (OK) periodontal pathogens Porphyromonas gingivalis, Fusobacterium nucleatum …

Porphyromonas gingivalis fimbrial protein Mfa5 contains a von Willebrand factor domain and an intramolecular isopeptide

TV Heidler, K Ernits, A Ziolkowska, R Claesson… - Communications …, 2021 - nature.com
… This needs to be studied further because the truncation of the vWF domain might obstruct
the correct formation of the other domains and thus its ability to bind to other fimbrial proteins. …