Potential COVID-19 therapeutics from a rare disease: weaponizing lipid dysregulation to combat viral infectivity

SL Sturley, T Rajakumar, N Hammond, K Higaki… - Journal of lipid …, 2020 - ASBMB
The coronavirus disease 2019 (COVID-19) pandemic caused by severe acute respiratory
syndrome coronavirus (SARS-CoV)-2 has resulted in the death of more than 328,000
persons worldwide in the first 5 months of 2020. Herculean efforts to rapidly design and
produce vaccines and other antiviral interventions are ongoing. However, newly evolving
viral mutations, the prospect of only temporary immunity, and a long path to regulatory
approval pose significant challenges and call for a common, readily available, and …
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