Genistein, a potential phytochemical against breast cancer treatment-insight into the molecular mechanisms
… inhibited cell division through the underlying mechanism of downregulating COX, topoisomerase
II enzyme TPA, and EROD protein activity [96]. Followed by angiogenesis, GNT (15–30 …
II enzyme TPA, and EROD protein activity [96]. Followed by angiogenesis, GNT (15–30 …
Genistein: a potent anti-breast cancer agent
…, KS Prasad, A Syed, P Reddy, CA Cull… - Current Issues in …, 2021 - mdpi.com
… -breast cancer drugs and genistein by inhibition of breast arterial calcifications. These
findings could lead to possibility of finding new combinations of chemotherapeutic drugs, along …
findings could lead to possibility of finding new combinations of chemotherapeutic drugs, along …
Genistein: its role in breast cancer growth and metastasis
V Mukund - Current drug metabolism, 2020 - ingentaconnect.com
… role is played by the Notch-1 pathway where the NF-κB inhibition activity by genistein is
induced in triple-negative breast cancer (TNBC), which is the worst type of breast cancer. …
induced in triple-negative breast cancer (TNBC), which is the worst type of breast cancer. …
Therapeutic potentials of genistein: New insights and perspectives
S Rasheed, K Rehman, M Shahid… - Journal of Food …, 2022 - Wiley Online Library
… In breast cancer, genistein can inhibit cell differentiation and proliferation, moreover, the
anti-cancer potential of genistein … -mediated AMPK activation proved as a potential therapeutic …
anti-cancer potential of genistein … -mediated AMPK activation proved as a potential therapeutic …
Molecular mechanisms of action of genistein in cancer: Recent advances
HS Tuli, MJ Tuorkey, F Thakral, K Sak… - Frontiers in …, 2019 - frontiersin.org
… have also surfaced as potential therapeutic targets of interest … MB-231 human breast cancer
cells, and decreased expression … By blocking it, whether by specific inhibitors or by genistein, …
cells, and decreased expression … By blocking it, whether by specific inhibitors or by genistein, …
Genistein as potential therapeutic candidate for menopausal symptoms and other related diseases
… highlight the known inhibitory effects of genistein regarding the … of genistein in breast cancer
cells are the NF-κB and AKT pathways [102,103]. Furthermore, genistein suppresses cancer …
cells are the NF-κB and AKT pathways [102,103]. Furthermore, genistein suppresses cancer …
Therapeutic effects of dietary soybean genistein on triple-negative breast cancer via regulation of epigenetic mechanisms
… mechanisms by which GE elicits its anti-carcinogenic properties involve inhibition of cellular
… differentiation, and cell cycle arrest at the G2-M phase [11,12,13]. Specifically, it is known to …
… differentiation, and cell cycle arrest at the G2-M phase [11,12,13]. Specifically, it is known to …
Cellular and molecular mechanisms of genistein in prevention and treatment of diseases: An overview
F Nazari‐Khanamiri… - Journal of Food …, 2021 - Wiley Online Library
… inhibition by genistein. According to the result of this study, genistein was understood as a
better inhibitor of NF-κB1 that plays a key role in the inhibition of breast cancer. The findings …
better inhibitor of NF-κB1 that plays a key role in the inhibition of breast cancer. The findings …
Genistein mediated molecular pharmacology, cell-specific anti-breast cancer mechanism with synergistic effect and in silico safety measurement
… anti-cancer mechanisms of Genistein in multiple BC cells were analyzed, mechanism of …
is an antibiotic that exhibits no inhibitory effects on Adriamycin resistance breast cancer cell. …
is an antibiotic that exhibits no inhibitory effects on Adriamycin resistance breast cancer cell. …
Molecular Pathways of Genistein Activity in Breast Cancer Cells
EK Konstantinou, A Gioxari, M Dimitriou… - International Journal of …, 2024 - mdpi.com
… Genistein is an inhibitor of the growth of breast cancer cell lines, MDA-468 (estrogen receptor
negative), and MCF-7 and MCF-7-D-40 (estrogen receptor positive) (IC 50 values ranging …
negative), and MCF-7 and MCF-7-D-40 (estrogen receptor positive) (IC 50 values ranging …