… benefit patients in clinical practice, through preventing or … achievement in the war against
cancer. It actually transformed … -line BCR-ABL tyrosine kinase inhibitor for CML patients losing …

… discuss the state of TDM in oncology. One of the conclusions of … recommendations to guide
optimal use in clinical practice, … oral agents such as tyrosine kinase inhibitors, and dose-…

… TDM as part of clinical routine in OAD cancer therapy. … With the approval of imatinib in 2001
[1], kinase inhibitors (KIs) … time intensive and thus difficult to implement in clinical practice. …

… inhibitors (MKIs), including the tyrosine kinase inhibitors (TKIs… in daily (hemato)-oncology
practice. Although the oral route … in oncology in managing DDIs is therapeutic drug monitoring …

… TDM in oncology has been previously advocated and for other targeted therapies, such as
kinase inhibitors, … drugs used in daily oncology practice and aimed to translate these data into …

… of molecularly targeted therapy in oncology, in which kinase inhibitors have continued to
be … Recent reviews on kinase inhibitors have described important aspects of kinase drug …

… or H2RAs is not recommended in clinical practice. If treatment … Finally, medical oncologists
able to understand AEs along … groups for therapeutic drug monitoring systems are needed, …

… therapies in oncology, based on therapeutic drug monitoring (… To overcome resistance,
newer generation kinase inhibitors … could be applied in clinical practice. b Example of proposed …

… Current National Comprehensive Cancer Network and the European Society for Medical
Oncology practice guidelines recommend that first-line treatment for patients with CLL should …

… has been used in clinical practice to individualize drug therapy since the beginning of the …
chemotherapy than men including immunotherapy and target therapy for cancer. Unger et al. …