[HTML][HTML] Alternative splicing during mammalian organ development
… during development and suggest a prominent role of microexons in early brain development.
… 3), we applied two-sided Fisher’s exact tests for all exons with devAS in at least one organ …
… 3), we applied two-sided Fisher’s exact tests for all exons with devAS in at least one organ …
Mechanisms of neuronal alternative splicing and strategies for therapeutic interventions
… in the brain to establish precise synaptic connections. … investigation of splicing regulators
and splicing mis-regulation in … of alternative splicing in the context of neuronal development, …
and splicing mis-regulation in … of alternative splicing in the context of neuronal development, …
Alternative splicing programming of axon formation
S Zheng - Wiley Interdisciplinary Reviews: RNA, 2020 - Wiley Online Library
… in the brain, where alternative splicing regulation is particularly pervasive and conserved.
Various aspects of brain development … precise temporal splicing control of this alternative exon. …
Various aspects of brain development … precise temporal splicing control of this alternative exon. …
RNA splicing regulators play critical roles in neurogenesis
… reinforces the hypothesis that alternative splicing is a significant … forming complex and precise
intercellular connections in the brain. This … roles in neurogenesis and brain development. …
intercellular connections in the brain. This … roles in neurogenesis and brain development. …
[HTML][HTML] Temporal dynamic analysis of alternative splicing during embryonic development in zebrafish
Z Liu, W Wang, X Li, X Zhao, H Zhao… - … and Developmental …, 2022 - frontiersin.org
… into the regulation of alternative splicing during embryogenesis in … Alternative splicing is
precisely regulated by the combination … Splicing factor NOVA2 regulates brain development by …
precisely regulated by the combination … Splicing factor NOVA2 regulates brain development by …
[HTML][HTML] Axonogenesis is coordinated by neuron-specific alternative splicing programming and splicing regulator PTBP2
… actin interaction, polymerization, and axon growth. Precocious … We conclude that
PTBP2-orchestrated alternative splicing … The exact determinants and precise hierarchy of …
PTBP2-orchestrated alternative splicing … The exact determinants and precise hierarchy of …
Complexity and graded regulation of neuronal cell-type–specific alternative splicing revealed by single-cell RNA sequencing
… the glutamatergic neuron-specific splicing program during brain development. … developmental
splicing switches in the brain, which are disrupted in myotonic dystrophy, but the exact cell …
splicing switches in the brain, which are disrupted in myotonic dystrophy, but the exact cell …
[HTML][HTML] Systematic exploration of dynamic splicing networks reveals conserved multistage regulators of neurogenesis
… how an alternative exon in a widely expressed splicing factor orchestrates temporal control
over cell differentiation. … Alternative splicing as a regulator of development and tissue identity. …
over cell differentiation. … Alternative splicing as a regulator of development and tissue identity. …
Alternative splicing of neuronal genes: new mechanisms and new therapies
D Lipscombe, EJL Soto - Current opinion in neurobiology, 2019 - Elsevier
… As discussed, for technologies to correct and to control alternative splicing … regulate
alternative splicing of neural genes. Knowing the cell-specific signals and proteins that control RNA …
alternative splicing of neural genes. Knowing the cell-specific signals and proteins that control RNA …
[HTML][HTML] miRNA-based regulation of alternative RNA splicing in Metazoans
AL Schorr, M Mangone - International journal of molecular sciences, 2021 - mdpi.com
… Unfortunately, while very important, the exact RNA splicing … beyond alternative RNA splicing
in which SRSF1 is involved. … is implicated in mammalian neuronal development, myoblast …
in which SRSF1 is involved. … is implicated in mammalian neuronal development, myoblast …