Conversion of extracellular ATP into adenosine: a master switch in renal health and disease

KM Dwyer, BK Kishore, SC Robson - Nature Reviews Nephrology, 2020 - nature.com
ATP maintains energy homeostasis and metabolism 1 and is … hydrolyses ATP or ADP; CD39L1
preferentially hydrolyses ADP overATP is released into the extracellular space upon cell …

Adenosine metabolism in the vascular system

GG Yegutkin - Biochemical Pharmacology, 2021 - Elsevier
… , extracellular ATP and its metabolites ADP and adenosine … an overview of
extracellular ADO metabolism in the vascular … on the cell surface followed by preferential “hand-to-hand” …

The yin and yang functions of extracellular ATP and adenosine in tumor immunity

L Feng, Y Cai, M Zhu, L Xing, X Wang - Cancer cell international, 2020 - Springer
… The roles of ATP were depending upon the concentration of … ATP is the preferred ligand only
for P2Y11R. For other P2YRs… , targeting their signaling pathways and their metabolism has …

Extracellular adenosine 5′-triphosphate in pulmonary disorders

A Pelleg - Biochemical Pharmacology, 2021 - Elsevier
… of ATP in bronchoalveolar lavage (BAL) fluid after allergen … shown that ATP-MgCl2 is a
safe, effective, and preferential … only of ATP’s role in intracellular energetics and metabolism. …

Increased host ATP efflux and its conversion to extracellular adenosine is crucial for establishing Leishmania infection

M Basu, P Gupta, A Dutta, K Jana… - Journal of cell …, 2020 - journals.biologists.com
… Accordingly, upon infection, we show here that ATP is … The main source of ATP is the
catabolic part of carbohydrate … that ATP produced through altered host cell metabolism not only …

[HTML][HTML] Adenosine metabolism: emerging concepts for cancer therapy

D Boison, GG Yegutkin - Cancer cell, 2019 - cell.com
… of extracellular ATP via reversible phosphotransfer reactions. Intracellular adenosine
metabolism … However, additional nucleotides and related compounds also serve as preferred

… -bridge method to assess extracellular metabolism of adenine nucleotides: detection of a possible role for purine nucleoside phosphorylase in adenosine metabolism

EK Jackson, DG Gillespie, D Cheng, Z Mi… - Purinergic …, 2020 - Springer
… for ATP and ADP suppress ionization in the ion source of mass … of ATP and its downstream
metabolites were determined after … to track the extracellular metabolism of ATP, we applied 10 …

Metabolic aspects of adenosine functions in the brain

M Garcia-Gil, M Camici, S Allegrini, R Pesi… - Frontiers in …, 2021 - frontiersin.org
… of components of the adenosine metabolism in learning and of the … When extracellular
adenosine generated from ATP … converted to adenosine only after the disappearance of ATP and …

[HTML][HTML] ATP and adenosine: Role in the immunopathogenesis of rheumatoid arthritis

JLG da Silva, DF Passos, VM Bernardes, DBR Leal - Immunology Letters, 2019 - Elsevier
release, metabolism, and the effects of binding of ATP and … autoimmune disease which
preferentially affects small peripheral … release adenosine triphosphate (ATP) into the extracellular

Extracellular cAMP-adenosine pathway signaling: a potential therapeutic target in chronic inflammatory airway diseases

ESA Pacini, NA Satori, EK Jackson… - Frontiers in …, 2022 - frontiersin.org
… stimuli, extracellular ATP is released from damaged cells … A 1 and A 3 receptors are
preferentially coupled to the … is mediated by the metabolism of extracellular NAD + to adenosine by …