… pre-maturation phase prior to IVM (pre-IVM) whereby COCs are held in meiotic arrest using
a cAMP- or cGMP-modulating … Furthermore, oocyte and cumulus cell gene expression levels …

… cyclic adenosine monophosphate (cAMP) level in cumulus-oocyte complexes (COCs) and
on oocyte … (Forskolin and IBMX) to detect the changes in intra-COCs cAMP after pre-IVM for 2 …

… meiotic arrest during a pre-maturation culture phase (pre-IVM… This does not alter our adherence
to PLOS ONE policies on … The physiological cAMP modulator in the ovary, CNP, can be …

… on modulation of cyclic adenosine 3 0 ,5 0 -monophosphate (cAMP… the dynamic changes in
oocyte chromatin remodeling. … of prematuration creates a capacitation window for the oocyte. …

… of oocytes from the natural follicular environment leads to a premature decline in intra-oocyte
cyclic adenosine monophosphate (… However, unexpectedly, no obvious changes were …

… The pre-IVM steps are known as pre-maturation or … of somatic cells’ gene expression and
metabolic changes, thereby … oocyte maturation in animal models because this modulator can …

… , on the cyclic guanosine monophosphate nucleotide (cGMP) … Immature oocytes have dense
layers of cumulus cells. Thus, … gene expression changes in freshly isolated oocytes, before …

… Regulation and modulation of oocyte maturation in the bovine… result of oocytes in GV stage
in time of pre-maturation where … However, we did not observe changes in relative abundance …

… cell CNPs function as oocyte maturation inhibitors by further increasing cGMP levels in
cumulus cells and the oocyte… that underwent pre-IVM incubation with the cAMP modulators FSK …

… [26] evaluated the role of cyclic AMP modulators added to pre… , the oocyte cannot remain
under the influence of cumulus cells … In this way, a phase of prematuration of immature oocytes …