[HTML][HTML] Vitamin D supplements and prevention of cancer and cardiovascular disease

…, D Gordon, T Copeland, D D'Agostino… - … England Journal of …, 2019 - Mass Medical Soc
… Randomization to receive vitamin D, n−3 fatty acids, both active agents, or both placebos
took place from November 2011 through March 2014. The trial intervention ended as planned …

… vs standard-dose vitamin D3 supplementation on progression-free survival among patients with advanced or metastatic colorectal cancer: the SUNSHINE randomized …

…, D Schrag, R Miksad, AJ Bullock, J Allen, D Zuckerman… - Jama, 2019 - jamanetwork.com
… for skeletal health, research has shown that 1α-hydroxylase (which converts 25-hydroxyvitamin
D into active 1,25-dihydroxyvitamin D 3 ) and the vitamin D receptor are present in most …

[HTML][HTML] Vitamin D supplementation and prevention of cardiovascular disease and cancer in the Finnish Vitamin D Trial: a randomized controlled trial

JK Virtanen, T Nurmi, A Aro… - The American journal of …, 2022 - Elsevier
… 25(OH)D is metabolized to the physiologically active form 1,… vitamin D supplementation and
in most trials the vitamin D dose was too low to induce significant changes in serum 25(OH)D

Effect of vitamin D3 supplements on development of advanced cancer: a secondary analysis of the VITAL randomized clinical trial

PD Chandler, WY Chen, ON Ajala, A Hazra… - JAMA network …, 2020 - jamanetwork.com
… acids (1 g/d) for primary prevention of cancer and cardiovascular … to receive vitamin D 3 ,
marine omega-3 fatty acids, both active … the mean BMI for active vitamin D vs placebo within the …

Vitamin D receptor activation protects against lipopolysaccharide-induced acute kidney injury through suppression of tubular cell apoptosis

J Du, S Jiang, Z Hu, S Tang, Y Sun… - … Physiology-Renal …, 2019 - journals.physiology.org
Kidney cell apoptosis was examined by TUNEL staining … paricalcitol, an active low-calcemic
vitamin D analog, before … for vitamin D protection against sepsis-associated renal injury. The …

Vitamin D signaling in inflammation and cancer: Molecular mechanisms and therapeutic implications

A El-Sharkawy, A Malki - Molecules, 2020 - mdpi.com
… of vitamin D analogues or the active metabolite of vitamin D … potential of vitamin D and its
analogs in the prevention and … squamous cell carcinoma [185], as well as in several human …

Role of vitamin D status in diabetic patients with renal disease

…, A Salvo, R Siligato, A Laudani, M Buemi, D Santoro - Medicina, 2019 - mdpi.com
active form of vitamin D, through its nuclear vitamin D receptor (VDR), modulates the expression
of about 1500 genes in numerous cellvitamin D represents a pivotal strategy to prevent

[HTML][HTML] Vitamin D supplementation and total cancer incidence and mortality: a meta-analysis of randomized controlled trials

N Keum, DH Lee, DC Greenwood, JE Manson… - Annals of …, 2019 - Elsevier
… In 2014, the US Preventive Services Task Force concluded that data were insufficient to …
effectiveness of vitamin D supplementation for cancer or cardiovascular disease prevention [25]. …

Vitamin D binding protein and the biological activity of vitamin D

RF Chun, A Shieh, C Gottlieb, V Yacoubian… - Frontiers in …, 2019 - frontiersin.org
… 1,25(OH) 2 D is the active vitamin D molecule with 25(OH)D being its immediate precursor
(… Prevention of nutritional rickets in children and osteomalacia in adults is the primary concern …

The emerging role of vitamin D and vitamin D receptor in diabetic nephropathy

M Lei, Z Liu, J Guo - BioMed research international, 2020 - Wiley Online Library
… with the active form 1,25(OH) 2 D 3 , has … vitamin D (VD) and its analogs have impressive
kidney-protective effects, such as antiproteinuria, antifibrosis, anti-inflammatory, and preventing