MCP-1: Function, regulation, and involvement in disease

S Singh, D Anshita, V Ravichandiran - International immunopharmacology, 2021 - Elsevier
oxidative stress in several studies. MCP-1 deficient mice have shown to produce less oxidative
… of hepatocellular carcinoma include chronic liver disease and cirrhosis associated with …

Lactobacillus rhamnosus GG Ameliorates Liver Injury and Hypoxic Hepatitis in Rat Model of CLP-Induced Sepsis

L Ding, Y Gong, Z Yang, B Zou, X Liu, B Zhang… - Digestive diseases and …, 2019 - Springer
… to oxidative stress [25]. In this study, therefore, oxidative stress and lipid peroxidation in the
liver were … of LGG-induced protection against sepsis-induced liver hypoxia (Fig. 4). Levels of …

[HTML][HTML] Protective effects of an anti-4-HNE monoclonal antibody against liver injury and lethality of endotoxemia in mice

H Qiao, Y Morioka, D Wang, K Liu, S Gao… - European Journal of …, 2023 - Elsevier
… to be elevated during oxidative stress. During systemic … -induced endotoxemia and liver injury
in mice. Endotoxic lethality in … the Ab conferred protection against brain injuries induced by …

[HTML][HTML] Evaluation of Liver Toxicity of Neonates Following Intragastric Administration or Intratracheal Instillation of Polyethylene Microplatics to Pregnant Mice

GW Kim, CY Kim - 2022 - e-jehs.org
… Conclusions: Despite the difficulty in comparing the toxic intensity between intragastric …
study revealed that oxidative stress and inflammation were induced in the neonatal liver. However…

Role of MCP-1 and CCR2 in alcohol neurotoxicity

K Zhang, J Luo - Pharmacological research, 2019 - Elsevier
… spinal cord among wild type, MCP-1 deficient (MCP-1 −/− ) … offered better protection against
alcohol-induced damage to … -1/CCR2 signaling, ER stress, and oxidative stress, as well as …

CCR2 and CCR5 promote diclofenac-induced hepatotoxicity in mice

Z He, G Wei, N Li, M Niu, S Gong, G Wu… - Naunyn-Schmiedeberg's …, 2019 - Springer
… factors, oxidative stress, and mitochondrial injury have been … , mice showed protection from
diclofenac-induced liver injury. … CYPs, had been implicated in the toxicity. Diclofenac (DIC) is …

Functional roles of chemokine receptor CCR2 and its ligands in liver disease

S She, L Ren, P Chen, M Wang, D Chen… - Frontiers in …, 2022 - frontiersin.org
liver disease, … chronic liver disease progression, suggesting that the CCL2/CCR2 axis may
be a promising therapeutic target for treating human liver diseases, especially the prevention

Comparison of cytokine levels in prostatic secretion between the IIIa and IIIb subtypes of prostatitis

CL Han, YX Deng, P Hu, BT Hu, T Wang… - Asian Journal of …, 2024 - journals.lww.com
… Several other studies have found that MCP-1 regulates oxidative stress. There were fewer
oxidative stress-associated products (ROS and 4-hydroxy-2-nonenal) in MCP-1-deficient mice

Macrophage phenotype and fibrosis in diabetic nephropathy

P Calle, G Hotter - International Journal of Molecular Sciences, 2020 - mdpi.com
… mechanisms, including oxidative stress, inflammatory cells … In fact, MCP-1 deficient diabetic
mice do not develop … , causing protection from kidney ischemia–reperfusion injury [84]. …

[HTML][HTML] Mechanisms of regenerative preconditioning in pigs with subtotal hepatectomies

MI Orue-Echebarria, J Vaquero, E Vara, L Rancan… - Cirugía y …, 2022 - scielo.org.mx
… with hepatocytes in a “quiescent” state, representing a potential approach to prevent the
post-hepatectomy liver failure. Portal vein ligation (PVL) or embolization (PVE) are well-known …