[HTML][HTML] Expectancy-related changes in dopaminergic error signals are impaired by cocaine self-administration

YK Takahashi, TA Stalnaker, Y Marrero-Garcia… - Neuron, 2019 - cell.com
… these teaching signals are disrupted by prior cocaine use … processing in prefrontal and
striatal regions. This altered … effect on reward-evoked and cue-evoked firing in the cocaine-…

[HTML][HTML] Reduced neural encoding of utility prediction errors in cocaine addiction

AB Konova, AO Ceceli, G Horga, SJ Moeller… - Neuron, 2023 - cell.com
… that addiction may fundamentally disrupt PE signaling and … Specifically, chronic self-administration
of cocaine appears to … attenuated ventral striatal PE encoding in the former. We …

… task increases sensitivity to cocaine self-administration and suppresses dopamine efflux in nucleus accumbens: support for the reward deficiency hypothesis of …

JMN Ferland, TJ Hynes, CD Hounjet… - Journal of …, 2019 - Soc Neuroscience
… -dependent human subjects show blunted DA release within the ventral striatum, encompassing
the NAc, after amphetamine administration, and have lower ratings of euphoria after …

[HTML][HTML] Withdrawal from escalated cocaine self-administration impairs reversal learning by disrupting the effects of negative feedback on reward exploitation: a …

P Zhukovsky, M Puaud, B Jupp, J Sala-Bayo… - …, 2019 - nature.com
… in an open field prior to acquisition of cocaine SA over six … effects of cocaine on the expression
of genes encoding DA … expression in the ventral striatum after long-access cocaine SA [93]…

[HTML][HTML] Prior cocaine self-administration impairs attention signals in anterior cingulate cortex

D Vázquez, HJ Pribut, AC Burton… - …, 2020 - nature.com
… in striatal and dopamine circuits that give rise to reward predictions and … Cocaine disrupts
NAc’s ability to encode reward predictions and expectancies during delays preceding reward

[HTML][HTML] Prior cocaine exposure increases firing to immediate reward while attenuating cue and context signals related to reward value in the insula

HJ Pribut, D Vázquez, AT Brockett, AD Wei… - Journal of …, 2021 - Soc Neuroscience
… to reward processing would be disrupted by chronic cocaine … that cocaine self-administration
diminished value encoding … after cocaine exposure held onto the expectation that reward

[HTML][HTML] The tubular striatum and nucleus accumbens distinctly represent reward-taking and reward-seeking

KN Wright, DW Wesson - Journal of Neurophysiology, 2021 - journals.physiology.org
… TuS ventral striatum subregions distinctly represent reward-… of rats engaged in a cue-guided
sucrose self-administration … synaptic alterations thought to encode information related to …

Modulation of memory consolidation by heroin and heroin conditioned stimuli: roles of expectation and dopamine D1 receptor?

T Francis, F Leri - 2023 - researchsquare.com
… that could be encoding the anticipation of drug effects. … µl/infusion because of previous
self-administration studies in our … is interpreted as a disruption of memory modulation by heroin …

Context-dependent and context-independent effects of D1 receptor antagonism in the basolateral and central amygdala during cocaine self-administration

ES Kim, KM Lattal - Eneuro, 2019 - eneuro.org
… the BLA or CeA disrupted stable cocaine self-administration. The … Previous research has
shown that striatal levels spike at 30 … to suggest the BLA to encode outcome value with specific …

Prior cocaine self-administration does not impair the ability to delay gratification in rats during diminishing returns

HJ Pribut, N Kang, MR Roesch - Behavioural Pharmacology, 2024 - journals.lww.com
Cocaine exposure also disrupts insula’s cue-encoding and … , cocaine reduces reward
expectancy signals in the ventral … in attention, context, reward and associative encoding across …