Kidney diseases
Z Zheng, J Geng, Y Jiang, M Zhang, R Yang… - Clinical Molecular …, 2021 - Springer
… showed that IgG and C3 were deposited along the capillary … that may be primary with a
disease specific to the kidneys or … with interstitial nephritis are often the predisposing factors for …
disease specific to the kidneys or … with interstitial nephritis are often the predisposing factors for …
[HTML][HTML] Recurrent glomerular diseases in renal transplantation with focus on role of electron microscopy
SV Seshan, SP Salvatore - Glomerular Diseases, 2021 - karger.com
… common primary glomerular diseases such as IgA nephropathy, membranous glomerulonephritis
(MGN), and diabetic kidney disease (… C3 deposits, and the 2 common entities that are …
(MGN), and diabetic kidney disease (… C3 deposits, and the 2 common entities that are …
Characteristics and genetic analysis of patients suspected with early-onset systemic lupus erythematosus
WF Lee, WL Fan, MH Tseng, HY Yang, JL Huang… - Pediatric …, 2022 - Springer
… profound glomerulonephritis with full-house glomerular deposits as … Genomic deoxyribonucleic
acid (DNA) was isolated from … glomerulonephritis with strong IgG, IgA, IgM, C3 and C1q …
acid (DNA) was isolated from … glomerulonephritis with strong IgG, IgA, IgM, C3 and C1q …
Complementopathies and precision medicine
E Gavriilaki, RA Brodsky - The Journal of clinical …, 2020 - Am Soc Clin Investig
… Membrane-bound C3 convertase then cleaves additional C3 to generate more C3b deposits,
closing the … Primary CAD is a clonal B cell lymphoproliferative disorder that is also called …
closing the … Primary CAD is a clonal B cell lymphoproliferative disorder that is also called …
Drug repurposing for glomerular diseases: an underutilized resource
… Atypical haemolytic uraemic syndrome, dense deposit disease and C3 glomerulonephritis
… IgAN receiving dapagliflozin had 71% risk reduction in the primary composite end point of …
… IgAN receiving dapagliflozin had 71% risk reduction in the primary composite end point of …
Complement in ANCA vasculitis, insights on pathophysiology and targeted therapies
V Srinivisa - Medical Research Archives, 2024 - esmed.org
… of C3 glomerulopathy and atypical haemolytic uraemic … In the 1980s, C3 glomerular deposits
were reported in patients … The primary outcome of the study was remission, defined as a …
were reported in patients … The primary outcome of the study was remission, defined as a …
Urinalysis and Diagnostic Tests
RSBA Goldfarb-Rumyantzev… - Clinical Handbook of …, 2023 - books.google.com
… Uses: Provides enhanced contrast of object edges and of … is the most common form of
primary glomerulonephritis, with as … complex MPGN if Ig and/or C3 deposits are found on IF, …
primary glomerulonephritis, with as … complex MPGN if Ig and/or C3 deposits are found on IF, …
Complement in human disease: approved and up-and-coming therapeutics
EE West, T Woodruff, V Fremeaux-Bacchi, C Kemper - The Lancet, 2023 - thelancet.com
… initiates the breakdown of deposited C3b and C4b together … and atypical haemolytic
uremic syndrome and other … The published core primary report clinical data used for FDA …
uremic syndrome and other … The published core primary report clinical data used for FDA …
Complement testing in the clinical laboratory
MAV Willrich, KMP Braun, AM Moyer… - Critical reviews in …, 2021 - Taylor & Francis
… converge at the C3 component and share the terminal pathway. … Factor H (FH) is the primary
regulator of the AP, blocking C3 … dense deposit disease (DDD) and C3 glomerulonephritis (…
regulator of the AP, blocking C3 … dense deposit disease (DDD) and C3 glomerulonephritis (…
Vascular occlusion in kidney biopsy is characteristic of clinically manifesting thrombotic microangiopathy
M Kovala, M Seppälä, K Kaartinen, S Meri… - Journal of clinical …, 2022 - mdpi.com
… these entities pathophysiologically [10]. In aHUS, … Later, primary goat anti-factor H antibody
was added into the … mutation in the C3 gene and a heterozygous risk haplotype in MCP…
was added into the … mutation in the C3 gene and a heterozygous risk haplotype in MCP…